The blood–brain barrier in psychosis

TA Pollak, S Drndarski, JM Stone, AS David… - The Lancet …, 2018 - thelancet.com
Blood–brain barrier pathology is recognised as a central factor in the development of many
neurological disorders, but much less is known about the role of the blood–brain barrier in …

Pharmacokinetic characteristics of long-acting injectable antipsychotics for schizophrenia: an overview

CU Correll, E Kim, JK Sliwa, W Hamm, S Gopal… - CNS drugs, 2021 - Springer
The availability of long-acting injectable (LAI) antipsychotics for the treatment of
schizophrenia provides clinicians with options that deliver continuous drug exposure and …

[图书][B] The American Psychiatric Association practice guideline for the treatment of patients with schizophrenia

American Psychiatric Association - 2020 - books.google.com
The American Psychiatric Association Practice Guideline for the Treatment of Patients With
Schizophrenia seeks to reduce these substantial psychosocial and public health …

Antipsychotic medication for women with schizophrenia spectrum disorders

BA Brand, YRA Haveman, F De Beer… - Psychological …, 2022 - cambridge.org
There are significant differences between men and women in the efficacy and tolerability of
antipsychotic drugs. Here, we provide a comprehensive overview of what is currently known …

ABC transporters at the blood–brain barrier

A Mahringer, G Fricker - Expert opinion on drug metabolism & …, 2016 - Taylor & Francis
Introduction: The blood–brain barrier (BBB) possesses an outstanding ability to protect the
brain against xenobiotics and potentially poisonous metabolites. Owing to this, ATP binding …

Assessing drug-drug interactions through therapeutic drug monitoring when administering oral second-generation antipsychotics

E Spina, C Hiemke, J de Leon - Expert opinion on drug metabolism …, 2016 - Taylor & Francis
ABSTRACT Introduction: Second-generation antipsychotics (SGAs) are frequently co-
prescribed with drug metabolic inducers and inhibitors. SGA pharmacokinetic drug-drug …

Clinically significant pharmacokinetic drug interactions of antiepileptic drugs with new antidepressants and new antipsychotics

E Spina, F Pisani, J de Leon - Pharmacological research, 2016 - Elsevier
Antiepileptic drugs (AEDs) are frequently co-prescribed with new antidepressants (ADs) or
new antipsychotics (APs). A PubMed search with no time limit was used to update the review …

Clinically relevant interactions between newer antidepressants and second-generation antipsychotics

E Spina, J de Leon - Expert Opinion on Drug Metabolism & …, 2014 - Taylor & Francis
Introduction: Combinations of newer antidepressants and second-generation antipsychotics
(SGAs) are frequently used by clinicians. Pharmacokinetic drug interaction (PK DI) and …

Clinically significant drug interactions with atypical antipsychotics

WK Kennedy, MW Jann, EC Kutscher - CNS drugs, 2013 - Springer
Atypical antipsychotics [also known as second-generation antipsychotics (SGAs)] have
become a mainstay therapeutic treatment intervention for patients with schizophrenia …

Classics in chemical neuroscience: risperidone

TC Chopko, CW Lindsley - ACS chemical neuroscience, 2018 - ACS Publications
After the identification of the influence of serotonergic receptors in ameliorating the negative
symptoms associated with schizophrenia, atypical antipsychotics were developed by …