[HTML][HTML] Mechanisms of COVID-19 associated pulmonary thrombosis: a narrative review
COVID-19, the infectious disease caused by severe acute respiratory syndrome coronavirus-
2 (SARS-CoV-2), is frequently associated with pulmonary thrombotic events, especially in …
2 (SARS-CoV-2), is frequently associated with pulmonary thrombotic events, especially in …
[HTML][HTML] Recombinant SARS-CoV-2 spike protein stimulates secretion of chymase, tryptase, and IL-1β from human mast cells, augmented by IL-33
I Tsilioni, TC Theoharides - International Journal of Molecular Sciences, 2023 - mdpi.com
SARS-CoV-2 infects cells via its spike (S) protein binding to its surface receptor angiotensin-
converting enzyme 2 (ACE2) and results in the production of multiple proinflammatory …
converting enzyme 2 (ACE2) and results in the production of multiple proinflammatory …
[HTML][HTML] Dysregulated early transcriptional signatures linked to mast cell and interferon responses are implicated in COVID-19 severity
R MacCann, AAG Leon, G Gonzalez, MJ Carr… - Frontiers in …, 2023 - frontiersin.org
Background Dysregulated immune responses to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection are thought to underlie the progression of coronavirus …
coronavirus 2 (SARS-CoV-2) infection are thought to underlie the progression of coronavirus …
[HTML][HTML] Tumor lineage-specific immune response in brain metastatic disease: opportunities for targeted immunotherapy regimen?
S Najjary, JM Kros, W de Koning, D Vadgama… - Acta neuropathologica …, 2023 - Springer
Metastases in the brain are the most severe and devastating complication of cancer. The
incidence of brain metastasis is increasing. Therefore, the need of finding specific druggable …
incidence of brain metastasis is increasing. Therefore, the need of finding specific druggable …
[HTML][HTML] The plasma proteome differentiates the multisystem inflammatory syndrome in children (MIS-C) from children with SARS-CoV-2 negative sepsis
Abstract Background The Multi-System Inflammatory Syndrome in Children (MIS-C) can
develop several weeks after SARS-CoV-2 infection and requires a distinct treatment …
develop several weeks after SARS-CoV-2 infection and requires a distinct treatment …
[HTML][HTML] Unlocking molecular mechanisms and identifying druggable targets in matched-paired brain metastasis of breast and lung cancers
S Najjary, W de Koning, JM Kros… - Frontiers in …, 2023 - frontiersin.org
Introduction The incidence of brain metastases in cancer patients is increasing, with lung
and breast cancer being the most common sources. Despite advancements in targeted …
and breast cancer being the most common sources. Despite advancements in targeted …
[HTML][HTML] Identification and validation of chemokine system-related genes in idiopathic pulmonary fibrosis
T Zhao, X Wu, X Zhao, K Yao, X Li, J Ni - Frontiers in Immunology, 2023 - frontiersin.org
Background Idiopathic pulmonary fibrosis (IPF) is a chronic progressive interstitial lung
disease with limited therapeutic options. Recent studies have demonstrated that …
disease with limited therapeutic options. Recent studies have demonstrated that …
[PDF][PDF] Dysregulated early transcriptional signatures linked to mast cell and interferon responses are implicated in COVID-19 severity.
G Gonzalez, R MacCann, AA Garcia Leon, M Carr… - 2023 - hse.openrepository.com
Background: Dysregulated immune responses to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection are thought to underlie the progression of coronavirus …
coronavirus 2 (SARS-CoV-2) infection are thought to underlie the progression of coronavirus …