Organic synthesis is one of the most successful and useful disciplines of science and mainly
involves the construction of carbon-carbon bond (s) and carbon-heteroatom bond (s) and …

The synthetic strategies involving the construction and cleavage of a bond represent the
central theme in organic synthesis. The cleavage of a bond is achieved either by weakening …

The first catalytic enantioselective construction of a 3, 3′-pyrrolidinyldispirooxindole
scaffold has been established via organocatalytic asymmetric 1, 3-dipolar cycloadditions of …

Catalytic asymmetric construction of the biologically important spiro [pyrrolidin‐3, 2′‐
oxindole] scaffold with contiguous quaternary stereogenic centers in excellent …

An efficient and powerful organocatalytic cascade reaction was achieved for the synthesis of
biologically important chiral spiro [pyrrolidin-3, 2′-oxindoles] using very simple and readily …

Because of their definite or potential biological and pharmaceutical activities, spirooxindole
heterocycles have been widely studied, and there has occurred a research boom on routes …

1, 3-Dipolar cycloaddition reaction of 1-aryl-1H-pyrrole-2, 5-diones 1a-e with non-stabilized
azomethine ylides, generated in situ via decarboxylative condensation of isatins 2a–c and …

A series of dispiropyrrolidine bisoxindoles were synthesized via a multicomponent 1, 3-
dipolar cycloaddition reaction of isatin, sarcosine and isatylidene malononitrile in refluxing …

The chemistry phosphorus and sulfur ylides have been exploited for a facile, short and
efficient synthesis of 3-spirocyclopentene-and 3-spiropyrazole-2-oxindoles from E-and Z …

Alzheimer's disease is a neurodegenerative disorder that impacts memory, thinking, and
behavior, and currently, there is no effective cure available for its treatment. This study …