Anti-proliferative and antitumor activity of organotin (IV) compounds. An overview of the last decade and future perspectives

CN Banti, SK Hadjikakou, T Sismanoglu… - Journal of inorganic …, 2019 - Elsevier
Organotins (IV) exhibit significant in vitro anti-proliferative activity, while the in vivo tests are
encouraging. The recent reports on the anti-proliferative activity of organotin (IV) compounds …

Anticancer applications and recent investigations of metallodrugs based on gallium, tin and titanium

Y Ellahioui, S Prashar, S Gomez-Ruiz - Inorganics, 2017 - mdpi.com
For more than 100 years metal complexes have been extensively used in therapy and since
the discovery of cisplatin the research in this field has expanded exponentially. The scientific …

Synthesis, characterization, biological activity and molecular docking studies of novel organotin (IV) carboxylates

N Muhammad, M Ahmad, M Sirajuddin, Z Ali… - Frontiers in …, 2022 - frontiersin.org
Four new carboxylates complexes with general formula R2SnL2 and R3SnL, where R= n-
butyl (1, 3), methyl (2, 4) and L= 4-Chlorophenoxyacetate, were synthesized in significant …

Novel diphenyltin (IV) complexes with carboxylato N-functionalized 2-quinolone ligands: Synthesis, characterization and in vitro anticancer studies

MP Kasalović, S Jelača, D Maksimović-Ivanić… - Journal of Inorganic …, 2024 - Elsevier
Three new diphenyltin (IV) complexes, bis (3-(4-methyl-2-oxoquinolinyl-1 (2H)-yl)
propanoato) diphenyltin (IV)(1), bis (2-(4-methyl-2-oxoquinolin-1 (2H)-yl) ethanoato) …

Organotin (IV)‐Decorated Graphene Quantum Dots as Dual Platform for Molecular Imaging and Treatment of Triple Negative Breast Cancer

IJ Gómez, K Ovejero‐Paredes… - … A European Journal, 2023 - Wiley Online Library
The pharmacological activity of organotin (IV) complexes in cancer therapy is well
recognized but their large applicability is hampered by their poor water solubility. Hence …

Anticancer activity of organotin (IV) carboxylates

MK Amir, S Khan, A Shah, IS Butler - Inorganica Chimica Acta, 2014 - Elsevier
This article provides a critical review of the anticancer activity of organotin (IV) carboxylates
in the last five years. Most of the organotin (IV) carboxylates discussed in this review have …

Organotin (IV) dithiocarbamate compounds as anticancer agents: a review of syntheses and cytotoxicity studies

NA Abd Aziz, N Awang, KM Chan, NF Kamaludin… - Molecules, 2023 - mdpi.com
Organotin (IV) dithiocarbamate has recently received attention as a therapeutic agent
among organotin (IV) compounds. The individual properties of the organotin (IV) and …

Organotin (IV)‐loaded mesoporous silica as a biocompatible strategy in cancer treatment

MZ Bulatović, D Maksimović‐Ivanić… - Angewandte Chemie …, 2014 - Wiley Online Library
The strong therapeutic potential of an organotin (IV) compound loaded in nanostructured
silica (SBA‐15pSn) is demonstrated: B16 melanoma tumor growth in syngeneic C57BL/6 …

Triphenyltin (IV) carboxylates with exceptionally high cytotoxicity against different breast cancer cell lines

I Predarska, M Saoud, I Morgan, P Lönnecke… - Biomolecules, 2023 - mdpi.com
Organotin (IV) carboxylates are a class of compounds explored as alternatives to platinum-
containing chemotherapeutics due to propitious in vitro and in vivo results, and distinct …

Di-and tri-organotin (IV) complexes with 2-hydroxy-1-naphthaldehyde 5-chloro-2-hydroxybenzoylhydrazone: Synthesis, characterization and in vitro antitumor …

M Hong, H Yin, X Zhang, C Li, C Yue… - Journal of Organometallic …, 2013 - Elsevier
Series of new organotin (IV) complexes of the types R2SnL, R is Me (1), Ph (2), o-Cl–
C6H4CH2 (3); and [R3SnL]∞, R= n-Bu (4)(H2L= 2-hydroxy-1-naphthaldehyde 5-chloro-2 …