In the mosquito–human life cycle, the six species of malaria parasites infecting humans
(Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale wallickeri, Plasmodium …

Plasmodium species cause malaria by proliferating in human erythrocytes. Invasion of
immunologically privileged erythrocytes provides a relatively protective niche as well as …

Plasmodium vivax shows a strict host tropism for reticulocytes. We identified transferrin
receptor 1 (TfR1) as the receptor for P. vivax reticulocyte-binding protein 2b (PvRBP2b). We …

More than a century after the discovery of Plasmodium spp. parasites, the pathogenesis of
severe malaria is still not well understood. The majority of malaria cases are caused by …

Plasmodium knowlesi is a zoonotic malaria parasite that has gained increasing medical
interest over the past two decades. This zoonotic parasitic infection is prevalent in Southeast …

Heterochromatin-dependent gene silencing is central to the adaptation and survival of
Plasmodium falciparum malaria parasites, allowing clonally variant gene expression during …

Plasmodium vivax is the most geographically widespread cause of human malaria and is
responsible for the majority of cases outside of the African continent. While great progress …

Abstract Background While Malaysia has had great success in controlling Plasmodium
falciparum and Plasmodium vivax, notifications of Plasmodium malariae and the …

Iron deficiency and malaria have similar global distributions, and frequently co-exist in
pregnant women and young children. Where both conditions are prevalent, iron …

Malaria, schistosomiasis and leishmaniases are among the most prevalent tropical parasitic
diseases and each requires new innovative treatments. Targeting essential parasite …