Latest developments in metal complexes as anticancer agents

R Paprocka, M Wiese-Szadkowska… - Coordination Chemistry …, 2022 - Elsevier
Every year novel biologically active compounds are designed as antitumor agents. This
review covers and highlights some of the most important findings described during 2018 …

Exploring the potential of metallodrugs as chemotherapeutics for triple negative breast cancer

N Nayeem, M Contel - Chemistry–A European Journal, 2021 - Wiley Online Library
This review focuses on studies of coordination and organometallic compounds as potential
chemotherapeutics against triple negative breast cancer (TNBC) which has one of the …

Copper complexes with 1, 10-phenanthroline derivatives: Underlying factors affecting their cytotoxicity

P Nunes, I Correia, F Marques, AP Matos… - Inorganic …, 2020 - ACS Publications
The interpretation of in vitro cytotoxicity data of Cu (II)-1, 10-phenanthroline (phen)
complexes normally does not take into account the speciation that complexes undergo in …

Therapeutic potential of vanadium complexes with 1, 10-phenanthroline ligands, quo vadis? Fate of complexes in cell media and cancer cells

P Nunes, I Correia, I Cavaco, F Marques… - Journal of Inorganic …, 2021 - Elsevier
Abstract V IV O-complexes formulated as [V IV O (OSO 3)(phen) 2](1)(phen= 1, 10-
phenanthroline),[V IV O (OSO 3)(Me 2 phen) 2](2)(Me 2 phen= 4, 7-dimethyl-1, 10 …

[HTML][HTML] Anticancer properties of complexes derived from bidentate ligands

DI Ugwu, J Conradie - Journal of Inorganic Biochemistry, 2023 - Elsevier
Cancer is the abnormal division and multiplication of cells in an organ or tissue. It is the
second leading cause of death globally. There are various types of cancer such as prostate …

Copper (II) and oxidovanadium (IV) complexes of chromone Schiff bases as potential anticancer agents

P Nunes, Y Yildizhan, Z Adiguzel, F Marques… - JBIC Journal of …, 2022 - Springer
We report the synthesis, characterization and biological screening of new chromone Schiff
bases derived from the condensation of three 6-substituted-3-formyl-chromones with …

Coordination compounds of biogenic metals as cytotoxic agents in cancer therapy

DA Guk, OO Krasnovskaya… - Russian Chemical …, 2021 - iopscience.iop.org
The review summarizes the data on the structures and methods for the synthesis of
compounds with anticancer activity based on biogenic metals, which can replace platinum …

Hydrolytically Stable TiIV–Hydrazone-Based Metallodrugs: Protein Interaction and Anticancer Potential

G Sahu, K Sahu, SA Patra, D Mohapatra… - ACS Applied Bio …, 2023 - ACS Publications
In this work, three titanium (IV)[TiIV (L1–3) 2](1–3) complexes have been reported using
three different tridentate dibasic ONO donor hydrazone ligands, pyridine-4-carboxylic acid (3 …

Mo (VI) potential Metallodrugs: explaining the transport and cytotoxicity by chemical transformations

M Mohanty, G Sahu, A Banerjee, S Lima… - Inorganic …, 2022 - ACS Publications
The transport and cytotoxicity of molybdenum-based drugs have been explained with the
concept of chemical transformation, a very important idea in inorganic medicinal chemistry …

Investigation of molecular mechanisms underlying the antiproliferative effects of colchicine against PC3 prostate cancer cells

M Ergul, F Bakar-Ates - Toxicology in Vitro, 2021 - Elsevier
This work examined the cytotoxic effects of colchicine on PC3 cells and elucidated the
possible underlying mechanisms of its cytotoxicity. The cells were exposed to colchicine at …