Introduction: The availability of non-vitamin K antagonist oral anti-coagulants alongside
vitamin K antagonists has offered a variety of options for anti-coagulation, but has also …

Background Warfarin dose variability observed in patients is attributed to variation in genes
involved in the warfarin metabolic pathway. Genetic variation in CYP2C9 and VKORC1 has …

Multiple factors can impact warfarin therapy, including genetic variations in the drug‐
metabolizing enzyme cytochrome P450 2C9 (CYP2C9). Compared with individuals with the …

Stereochemistry has evinced the importance of many chiral drugs with respect to drug
designing and development. A literature review was conducted for several chiral drugs …

Aims The aims of this study are to apply a theory‐based mechanistic model to describe the
pharmacokinetics (PK) and pharmacodynamics (PD) of S‐and R‐warfarin. Methods Clinical …

The anticoagulant drug warfarin and the lipid-lowering statin drugs are commonly co-
administered to patients with cardiovascular diseases. Clinically significant drug-drug …

Ganciclovir is an antiviral drug that is mainly used in treating viral infections like
cytomegalovirus and many other infections. An electrochemical method was developed for …

Cranberry is a dietary supplement popularly used for the prophylaxis of urinary tract
infection. Interestingly, cranberry–warfarin interactions in clinical reports have shown …

Chronic kidney disease (CKD) complicates warfarin anticoagulation partially through its
effect on CYP2C9 activity. Tecarfarin, a novel vitamin K antagonist, is not metabolized by …

Purpose The combination of warfarin and compound Danshen dripping pill (CDDP) is
helpful for patients with both coronary heart disease (CHD) and atrial fibrillation (AF). The …