Linac coherent light source: The first five years
A new scientific frontier opened in 2009 with the start of operations of the world's first x-ray
free-electron laser (FEL), the Linac Coherent Light Source (LCLS), at SLAC National …
free-electron laser (FEL), the Linac Coherent Light Source (LCLS), at SLAC National …
[HTML][HTML] XFELs for structure and dynamics in biology
JCH Spence - IUCrJ, 2017 - scripts.iucr.org
The development and application of the free-electron X-ray laser (XFEL) to structure and
dynamics in biology since its inception in 2009 are reviewed. The research opportunities …
dynamics in biology since its inception in 2009 are reviewed. The research opportunities …
Fast and interpretable classification of small X-ray diffraction datasets using data augmentation and deep neural networks
X-ray diffraction (XRD) data acquisition and analysis is among the most time-consuming
steps in the development cycle of novel thin-film materials. We propose a machine learning …
steps in the development cycle of novel thin-film materials. We propose a machine learning …
[HTML][HTML] Cheetah: software for high-throughput reduction and analysis of serial femtosecond X-ray diffraction data
The emerging technique of serial X-ray diffraction, in which diffraction data are collected
from samples flowing across a pulsed X-ray source at repetition rates of 100 Hz or higher …
from samples flowing across a pulsed X-ray source at repetition rates of 100 Hz or higher …
Rapid identification of X-ray diffraction patterns based on very limited data by interpretable convolutional neural networks
Large volumes of data from material characterizations call for rapid and automatic data
analysis to accelerate materials discovery. Herein, we report a convolutional neural network …
analysis to accelerate materials discovery. Herein, we report a convolutional neural network …
Ultra-fast and ultra-intense x-ray sciences: first results from the Linac Coherent Light Source free-electron laser
X-ray free-electron lasers (FELs) produce femtosecond x-ray pulses with unprecedented
intensities that are uniquely suited for studying many phenomena in atomic, molecular, and …
intensities that are uniquely suited for studying many phenomena in atomic, molecular, and …
Correlations in scattered X-ray laser pulses reveal nanoscale structural features of viruses
We use extremely bright and ultrashort pulses from an x-ray free-electron laser (XFEL) to
measure correlations in x rays scattered from individual bioparticles. This allows us to go …
measure correlations in x rays scattered from individual bioparticles. This allows us to go …
Emerging opportunities in structural biology with X-ray free-electron lasers
I Schlichting, J Miao - Current opinion in structural biology, 2012 - Elsevier
X-ray free-electron lasers (X-FELs) produce X-ray pulses with extremely brilliant peak
intensity and ultrashort pulse duration. It has been proposed that radiation damage can be …
intensity and ultrashort pulse duration. It has been proposed that radiation damage can be …
3D diffractive imaging of nanoparticle ensembles using an x-ray laser
Single particle imaging at x-ray free electron lasers (XFELs) has the potential to determine
the structure and dynamics of single biomolecules at room temperature. Two major hurdles …
the structure and dynamics of single biomolecules at room temperature. Two major hurdles …
Low-signal limit of X-ray single particle diffractive imaging
An outstanding question in X-ray single particle imaging experiments has been the
feasibility of imaging sub 10-nm-sized biomolecules under realistic experimental conditions …
feasibility of imaging sub 10-nm-sized biomolecules under realistic experimental conditions …