Methodological breakthroughs over the past four decades have repeatedly revolutionized
transcriptome profiling. Using RNA sequencing (RNA-seq), it has now become possible to …

Abstract The International Molecular Exchange (IMEx) consortium is an international
collaboration between major public interaction data providers to share literature-curation …

Although the genes essential for life have been identified in less complex model organisms,
their elucidation in human cells has been hindered by technical barriers. We used extensive …

Meta-analysis of gene expression data sets is increasingly performed to help identify robust
molecular signatures and to gain insights into underlying biological processes. The …

The field of antibiotic drug discovery and the monitoring of new antibiotic resistance
elements have yet to fully exploit the power of the genome revolution. Despite the fact that …

Abstract InnateDB (http://www. innatedb. com) is an integrated analysis platform that has
been specifically designed to facilitate systems-level analyses of mammalian innate …

Finding the components of cellular circuits and determining their functions systematically
remains a major challenge in mammalian cells. Here, we introduced genome-wide pooled …

Middle East respiratory syndrome coronavirus (MERS-CoV) is a lineage C betacoronavirus,
and infections with this virus can result in acute respiratory syndrome with renal failure …

Abstract The Molecular INTeraction Database (MINT, http://mint. bio. uniroma2. it/mint/) is a
public repository for protein–protein interactions (PPI) reported in peer-reviewed journals …

IntAct is an open-source, open data molecular interaction database populated by data either
curated from the literature or from direct data depositions. Two levels of curation are now …