Bronchopulmonary dysplasia (BPD) is the most common cause of morbidity and mortality in
preterm infants. A key histopathological feature of BPD is stunted late lung development …

The incidence of preterm birth is increasing, leading to a growing population with potential
long-term pulmonary complications. Apnoea of prematurity (AOP) is one of the major …

Background Maximal expiratory airflow peaks early in the third decade of life, then gradually
declines with age. The pattern of airflow through adulthood for individuals born very preterm …

Background Lifelong pulmonary consequences of being born extremely preterm or with
extremely low birth weight remain unknown. We aimed to describe lung function trajectories …

Bronchopulmonary dysplasia (BPD) still carries a heavy burden of morbidity and mortality in
survivors of extreme prematurity. The disease is characterized by simplification of the …

Mesenchymal stem cells (MSCs) prevent the onset of bronchopulmonary dysplasia (BPD) in
animal models, an effect that seems to be mediated by their secreted extracellular vesicles …

Early therapeutic effect of intratracheally (IT)-administered extracellular vesicles secreted by
mesenchymal stem cells (MSC-EVs) has been demonstrated in a rat model of …

Objectives. 1. To review and discuss available evidence supporting that spirometry is an
overlooked global health marker, that could be used regularly through the lifespan to …

More and more very low birth weight (VLBW) infants around the world survive nowadays,
with consequently larger numbers of children developing prematurity-related morbidities …

Background Chronic obstructive pulmonary disease (COPD) in adults is a result of
environmental risk factors and genetic factors. Polygenic COPD risk scores are highly …