Covering: up to the end of 2021 [2+ 2]-Type cyclobutane natural products are
biosynthetically derived from intermolecular [2+ 2] cycloaddition or intramolecular [2+ 2] …

Covering: up to mid-2020 Terpenoids, also called isoprenoids, are the largest and most
structurally diverse family of natural products. Found in all domains of life, there are over 80 …

To reduce experimental effort associated with directed protein evolution and to explore the
sequence space encoded by mutating multiple positions simultaneously, we incorporate …

Plants synthesize numerous alkaloids that mimic animal neurotransmitters. The diversity of
alkaloid structures is achieved through the generation and tailoring of unique carbon …

Natural products possess structural complexity, diversity and chirality with attractive
functions and biological activities that have significantly impacted drug discovery initiatives …

Since the dawn of the 20th century, the average life expectancy at birth has nearly doubled
due to advances in science and medicine. As medical records grew more reliable, it became …

This study investigates the role of volatile organic compounds in systemic acquired
resistance (SAR), a salicylic acid (SA)-associated, broad-spectrum immune response in …

Chiral amines represent a prominent functional group in pharmaceuticals and
agrochemicals and are hence attractive targets for asymmetric synthesis. Since the …

Scaffold diversity is a crucial feature of compound collections that has a huge impact on their
success in biological screenings. The synthesis of highly complex and diverse scaffolds …

Covering: 2000 to 2014 This review covers conformational and configurational assignments
in natural product molecules using chiroptical spectroscopy reported over the last 15 years …