The expanding knowledge involving the cytokine transcription factor network has provided
new insights into the acute lung inflammatory response. There are numerous lung …

A polarized macrophage response is presumed to have a pivotal role in a variety of
immunological pathophysiology. However, the molecular mechanism underlying …

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are diseases with
high mortality. Macrophages and neutrophils are responsible for inflammatory responses in …

Asthma, chronic obstructive pulmonary disease, and cystic fibrosis are three chronic
pulmonary diseases that affect an estimated 420 million individuals across the globe. A key …

Background Axl is a cell surface receptor tyrosine kinase, and activation of the Axl
attenuates inflammation induced by various stimuli. Growth arrest-specific 6 (Gas6) has high …

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) confer substantial
morbidity and mortality, and have no specific therapy. The accessibility of the distal lung …

Background The ligand-activated transcription factor peroxisome proliferator-activated
receptor (PPAR) γ plays crucial roles in diverse biological processes including cellular …

Although uncontrolled inflammatory response plays a central role in the pathogenesis of
acute lung injury (ALI), the precise molecular mechanisms underlying the development of …

Objectives Glioma is one of the most aggressive brain tumours with poor overall survival
despite advanced technology in surgical resection, chemotherapy and radiation …

Suppressor of cytokine signaling 3 (SOCS3) is an important intracellular protein that inhibits
cytokine signaling in numerous cell types and has been implicated in several inflammatory …