The gut microbiome has been established as a key environmental factor to health. Genetic
influences on the gut microbiome have been reported, yet, doubts remain as to the …

Previously we have reported that metastatic melanoma cell lines and tumor specimens have
reduced expression of ADAR1 and consequently are impaired in their ability to perform A-to …

Abstract α-actinin superfamily houses the family of parvins, comprising α, β and γ isoforms in
the vertebrates and a single orthologue in the invertebrates. Parvin as an adaptor protein is …

Cofilin phospho-regulation is important for actin filament turnover and is implicated in
cancer. Phosphorylation of cofilin is mediated by LIM kinases (LIMKs) and …

Geminin, a DNA replication licensing inhibitor, ensures faithful DNA replication in
vertebrates. Several studies have shown that geminin depletion in vitro results in …

Abstract Two-dimensional (2D) materials such as MXenes, are usually well utilized in the
field of catalysts and battery due to their good hydrophilicity and diversified surface …

Integrin-linked kinase (ILK) forms a heterotrimeric protein complex with PINCH and PARVIN
(IPP) in Focal Adhesions (FAs) that acts as a signaling platform between the cell and its …

Background Glioblastoma multiforme (GBM) is characterized by widespread genetic and
transcriptional heterogeneity. Aberrant DNA methylation plays a vital role in GBM …

Actopaxin is a newly discovered focal adhesions (FAs) protein, actin-binding protein and
pseudopodia-enriched molecule. It can not only bind to a variety of FAs proteins (such as …

Legumain is a cysteine protease broadly associated with inflammation. It has been reported
to cleave and activate protease‐activated receptor 2 to provoke pain associated with oral …