[HTML][HTML] Curcumin as tyrosine kinase inhibitor in cancer treatment

A Golonko, H Lewandowska, R Świsłocka… - European Journal of …, 2019 - Elsevier
Curcumin is a natural substance known for ages, exhibiting a multidirectional effect in
cancer prevention and adjuvant cancer therapies. The great advantage of using …

Recent progress in anticancer agents incorporating pyrazole scaffold

S Mor, M Khatri, S Sindhu - Mini Reviews in Medicinal …, 2022 - ingentaconnect.com
The search for new anticancer agents is considered a dynamic field of medicinal chemistry.
In recent years, the synthesis of compounds with anticancer potential has increased and a …

Synthesis, spectral characterization, electronic structure and biological activity screening of the schiff base 4-((4-hydroxy-3-methoxy-5-Nitrobenzylidene) Amino)-N …

N Elangovan, R Thomas, S Sowrirajan… - Polycyclic Aromatic …, 2022 - Taylor & Francis
A new Schiff base was prepared by the condensation between the sulfa drug sulfadiazine
and 5-nitrovanilline to form 4-((4-hydroxy-3-methoxy-5-nitrobenzylidene) amino)-N …

The potency of heterocyclic curcumin analogues: An evidence-based review

FC Rodrigues, NVA Kumar, G Thakur - Pharmacological Research, 2021 - Elsevier
Curcumin, a potent phytochemical, has been a significant lead compound and has been
extensively investigated for its multiple bioactivities. Owing to its natural origin, non-toxic …

Natural tyrosine kinase inhibitors acting on the epidermal growth factor receptor: Their relevance for cancer therapy

Y Liang, T Zhang, J Zhang - Pharmacological Research, 2020 - Elsevier
Epidermal growth factor receptor (EGFR), also known as ErbB-1/HER-1, plays a key role in
the regulation of the cell proliferation, migration, differentiation, and survival. Since the …

Curcumin analogues and derivatives with anti-proliferative and anti-inflammatory activity: Structural characteristics and molecular targets

E Chainoglou, D Hadjipavlou-Litina - Expert opinion on drug …, 2019 - Taylor & Francis
ABSTRACT Introduction: Curcumin (Diferuloylmethane) is a natural phenolic compound,
which belongs to the curcuminoid family, presenting pleiotropic activity and low …

Curcumin a potent cancer preventive agent: Mechanisms of cancer cell killing

M Tuorkey - Interventional Medicine and Applied Science, 2014 - akjournals.com
There is no doubt that diet could effectively improve health and halt cancers. Dietary
phytochemical compounds and their derivatives represent a cornucopia of effectively …

Designing strategies, structural activity relationship and biological activity of recently developed nitrogen containing heterocyclic compounds as epidermal growth …

R Pal, G Teli, GSP Matada, PS Dhiwar - Journal of Molecular Structure, 2023 - Elsevier
Cancer cells have the ability of dysregulation and autonomous proliferation due to
unchecked production of definite molecules. These molecules are involved in the cell growth …

Modified curcumins as potential drug candidates for breast cancer: An overview

AL Flint, DW Hansen, LVD Brown, LE Stewart, E Ortiz… - Molecules, 2022 - mdpi.com
Breast cancer (BC), the most common malignancy in women, results from significant
alterations in genetic and epigenetic mechanisms that alter multiple signaling pathways in …

[PDF][PDF] Curcumin and curcuminoids: chemistry, structural studies and biological properties

J González-Albadalejo, D Sanz… - An. Real Acad. Nac …, 2015 - researchgate.net
This review concerns curcumin, a fascinating molecule that has a wide use in medicine for
diseases as significant as cancer and Alzheimer. The chemical and physicochemical …