Harnessing carbon monoxide-releasing platforms for cancer therapy

Y Zhou, W Yu, J Cao, H Gao - Biomaterials, 2020 - Elsevier
Carbon monoxide (CO) is a gaseous molecule that has drawn growing concerns for cancer
treatment, due to its multifaceted regulation of cellular function and the tumor …

Emerging delivery strategies of carbon monoxide for therapeutic applications: from CO gas to CO releasing nanomaterials

H Yan, J Du, S Zhu, G Nie, H Zhang, Z Gu, Y Zhao - Small, 2019 - Wiley Online Library
Carbon monoxide (CO) therapy has emerged as a hot topic under exploration in the field of
gas therapy as it shows the promise of treating various diseases. Due to the gaseous …

Oral nanotherapeutics of andrographolide/carbon monoxide donor for synergistically anti-inflammatory and pro-resolving treatment of ulcerative colitis

Y Zhou, M Yang, X Yan, L Zhang, N Lu… - … Applied Materials & …, 2023 - ACS Publications
Ulcerative colitis (UC) is a chronic inflammatory bowel disease of unknown etiology affecting
the colon and rectum. Current therapeutics are focused on suppressing inflammation but are …

Controlled therapeutic delivery of CO from carbon monoxide-releasing molecules (CORMs)

HI Choi, A Zeb, MS Kim, I Rana, N Khan… - Journal of Controlled …, 2022 - Elsevier
Carbon monoxide (CO) has been regarded as a “silent killer” for its toxicity toward biological
systems. However, a low concentration of endogenously produced CO has shown a number …

Simvastatin-loaded solid lipid nanoparticles for enhanced anti-hyperlipidemic activity in hyperlipidemia animal model

SZH Rizvi, FA Shah, N Khan, I Muhammad… - International journal of …, 2019 - Elsevier
The objective of current study was to develop solid lipid nanoparticles-loaded with
simvastatin (SIM-SLNs) and investigate their in vivo anti-hyperlipidemic activity in poloxamer …

Type-I Photosensitizer-Triggered Controllable Carbon Monoxide Release for Effective Treatment of Staph Skin Infection

L Cao, X Lin, X Liu, M Wu, S Liu, T Wang, D Mao… - Nano Letters, 2023 - ACS Publications
Staphylococcus aureus (S. aureus) infection is a major infectious skin disease that is highly
resistant to conventional antibiotic treatment and host immune defense, leading to …

Enhanced neuroprotective and antidepressant activity of curcumin-loaded nanostructured lipid carriers in lipopolysaccharide-induced depression and anxiety rat …

S Rubab, K Naeem, I Rana, N Khan, M Afridi… - International Journal of …, 2021 - Elsevier
The present study aims to develop curcumin-loaded nanostructured lipid carriers (CUR-
NLCs) and investigate their neuroprotective effects in lipopolysaccharide (LPS)-induced …

Nanostructured lipid carriers-mediated brain delivery of carbamazepine for improved in vivo anticonvulsant and anxiolytic activity

N Khan, FA Shah, I Rana, MM Ansari, F ud Din… - International journal of …, 2020 - Elsevier
The limited brain delivery of carbamezapine (CBZ) presents a major hurdle in the successful
epilepsy treatment. The potential of carbamezapine-loaded nanostructured lipid carriers …

Hydrogel containing solid lipid nanoparticles loaded with argan oil and simvastatin: Preparation, in vitro and ex vivo assessment

MFA Khan, A Ur. Rehman, H Howari, A Alhodaib… - Gels, 2022 - mdpi.com
Transdermal hydrogels have the potential to improve therapeutic outcomes via enhancing
bioavailability and reducing toxicity associated with oral delivery. The goal of the present …

[HTML][HTML] Preparation and characterization of solid lipid nanoparticles encapsulated noscapine and evaluation of its protective effects against imiquimod-induced …

P Rahmanian-Devin, VR Askari, Z Sanei-Far… - Biomedicine & …, 2023 - Elsevier
Psoriasis is a chronic inflammatory skin disease characterized by thickening the epidermis
with erythema, scaling, and proliferation. Noscapine (NOS) has several anti-inflammatory …