It has been 30 years since a'new'leukaemia termed adult T-cell leukaemia (ATL) was
described in Japan, and more than 25 years since the isolation of the retrovirus, human T …

The first human tumor virus was discovered in the middle of the last century by Anthony
Epstein, Bert Achong and Yvonne Barr in African pediatric patients with Burkitt's lymphoma …

The two general groups for tumors of the hemolymphatic system are lymphoid (lymphoma
and leukemia) and myeloid leukemias. The tumors in each can be characterized by their …

The transcription factor NF-κB is a tightly regulated positive mediator of T-and B-cell
development, proliferation, and survival. The controlled activity of NF-κB is required for the …

Human T-cell leukemia virus type 1 (HTLV-1) is the causal agent of a neoplastic disease of
CD4+ T cells, adult T-cell leukemia (ATL), and inflammatory diseases including HTLV-1 …

The human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus discovered to be
causative of a human cancer, adult T-cell leukemia. The transforming entity of HTLV-1 has …

HTLV-1 (Human T-cell lymphotropic virus type 1) is a complex human delta retrovirus that
currently infects 10–20 million people worldwide. While HTLV-1 infection is generally …

The human T-cell lymphotropic virus type 1 (HTLV-1) is the etiological agent of adult T-cell
leukemia/lymphoma (ATLL), a neoplasm of CD4+ CD25+ T cells that occurs in 2–5% of …

Adult T-cell leukemia/lymphoma (ATL) is an aggressive malignancy of mature activated T
cells caused by human T-cell lymphotropic virus type I. ATL carries a bad prognosis …

It has been nearly 40 years since human T-cell leukemia virus-1 (HTLV-1), the first
oncogenic retrovirus in humans and the first demonstrable cause of cancer by an infectious …