Copper (I)-catalyzed 1, 3-dipolar cycloaddition between organic azides and terminal
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …

Cu (I)-catalyzed azide–alkyne 1, 3-dipolar cycloaddition (CuAAC), popularly known as the
“click reaction”, serves as the most potent and highly dependable tool for facile construction …

Bacteria possess an extraordinary repertoire of cell envelope glycans that have critical
physiological functions. Pathogenic bacteria have glycans that are essential for growth and …

Chemistry, traditionally being the science of synthesis and structural manipulations of
molecules, has gradually undertaken the more challenging task of biology-oriented …

Interrogating biological systems is often limited by access to biological probes. The
emergence of “click chemistry” has revolutionized bioconjugate chemistry by providing facile …

Glycosylation is a fundamental co-translational and/or post-translational modification
process where an attachment of sugars onto either proteins or lipids can alter their biological …

Bacterial infections remain a global healthcare problem that is particularly attributed to the
spread of antibiotic resistance and the evolving pathogenicity. Accurate and swift …

Rod-shaped mycobacteria expand from their poles, yet d-amino acid probes label cell wall
peptidoglycan in this genus at both the poles and sidewall. We sought to clarify the …

The study of cellular glycosylation presents many challenges due, in large part, to the
nontemplated nature of glycan biosynthesis and glycans' structural complexity …

The cell surface is the essential interface between a bacterium and its surroundings.
Composed primarily of molecules that are not directly genetically encoded, this highly …