Diagnostics and correction of batch effects in large‐scale proteomic studies: a tutorial
Advancements in mass spectrometry‐based proteomics have enabled experiments
encompassing hundreds of samples. While these large sample sets deliver much‐needed …
encompassing hundreds of samples. While these large sample sets deliver much‐needed …
Mass spectrometry‐based high‐throughput proteomics and its role in biomedical studies and systems biology
There are multiple reasons why the next generation of biological and medical studies
require increasing numbers of samples. Biological systems are dynamic, and the effect of a …
require increasing numbers of samples. Biological systems are dynamic, and the effect of a …
[HTML][HTML] Impact of feature harmonization on radiogenomics analysis: Prediction of EGFR and KRAS mutations from non-small cell lung cancer PET/CT images
Objective To investigate the impact of harmonization on the performance of CT, PET, and
fused PET/CT radiomic features toward the prediction of mutations status, for epidermal …
fused PET/CT radiomic features toward the prediction of mutations status, for epidermal …
Nine quick tips for pathway enrichment analysis
Pathway enrichment analysis (PEA) is a computational biology method that identifies
biological functions that are overrepresented in a group of genes more than would be …
biological functions that are overrepresented in a group of genes more than would be …
Multi-omics approaches in psychoneuroimmunology and health research: conceptual considerations and methodological recommendations
The field of psychoneuroimmunology (PNI) has grown substantially in both relevance and
prominence over the past 40 years. Notwithstanding its impressive trajectory, a majority of …
prominence over the past 40 years. Notwithstanding its impressive trajectory, a majority of …
Treatment response prediction using MRI‐based pre‐, post‐, and delta‐radiomic features and machine learning algorithms in colorectal cancer
S Shayesteh, M Nazari, A Salahshour… - Medical …, 2021 - Wiley Online Library
Objectives We evaluate the feasibility of treatment response prediction using MRI‐based pre‐
, post‐, and delta‐radiomic features for locally advanced rectal cancer (LARC) patients …
, post‐, and delta‐radiomic features for locally advanced rectal cancer (LARC) patients …
Evaluating and minimizing batch effects in metabolomics
Determining metabolomic differences among samples of different phenotypes is a critical
component of metabolomics research. With the rapid advances in analytical tools such as …
component of metabolomics research. With the rapid advances in analytical tools such as …
Interpretation of omics data analyses
Omics studies attempt to extract meaningful messages from large-scale and high-
dimensional data sets by treating the data sets as a whole. The concept of treating data sets …
dimensional data sets by treating the data sets as a whole. The concept of treating data sets …
Proteomics of the Heart
OA Karpov, A Stotland, K Raedschelders… - Physiological …, 2024 - journals.physiology.org
Mass spectrometry-based proteomics is a sophisticated identification tool specializing in
portraying protein dynamics at a molecular level. Proteomics provides biologists with a …
portraying protein dynamics at a molecular level. Proteomics provides biologists with a …
[HTML][HTML] A High-Throughput PIXUL–Matrix-Based Toolbox to Profile Frozen and Formalin-Fixed Paraffin-Embedded Tissues Multiomes
Large-scale high-dimensional multiomics studies are essential to unravel molecular
complexity in health and disease. We developed an integrated system for tissue sampling …
complexity in health and disease. We developed an integrated system for tissue sampling …