Regulation of transposable elements by DNA modifications

Ö Deniz, JM Frost, MR Branco - Nature Reviews Genetics, 2019 - nature.com
Maintenance of genome stability requires control over the expression of transposable
elements (TEs), whose activity can have substantial deleterious effects on the host …

Perspectives and benefits of high-throughput long-read sequencing in microbial ecology

L Tedersoo, M Albertsen, S Anslan… - Applied and …, 2021 - Am Soc Microbiol
Short-read, high-throughput sequencing (HTS) methods have yielded numerous important
insights into microbial ecology and function. Yet, in many instances short-read HTS …

Fungi in aquatic ecosystems

HP Grossart, S Van den Wyngaert, M Kagami… - Nature Reviews …, 2019 - nature.com
Fungi are phylogenetically and functionally diverse ubiquitous components of almost all
ecosystems on Earth, including aquatic environments stretching from high montane lakes …

Means, mechanisms and consequences of adenine methylation in DNA

K Boulias, EL Greer - Nature Reviews Genetics, 2022 - nature.com
Abstract N 6-methyl-2′-deoxyadenosine (6mA or m6dA) has been reported in the DNA of
prokaryotes and eukaryotes ranging from unicellular protozoa and algae to multicellular …

[HTML][HTML] N6-methyladenine DNA modification in the human genome

CL Xiao, S Zhu, M He, D Chen, Q Zhang, Y Chen, G Yu… - Molecular cell, 2018 - cell.com
Summary DNA N 6-methyladenine (6mA) modification is the most prevalent DNA
modification in prokaryotes, but whether it exists in human cells and whether it plays a role in …

Species diversity, updated classification and divergence times of the phylum Mucoromycota

H Zhao, Y Nie, TK Zong, K Wang, ML Lv, YJ Cui… - Fungal Diversity, 2023 - Springer
Zygomycetes are phylogenetically early diverging, ecologically diverse, industrially
valuable, agriculturally beneficial, and clinically pathogenic fungi. Although new phyla and …

Critical assessment of DNA adenine methylation in eukaryotes using quantitative deconvolution

Y Kong, L Cao, G Deikus, Y Fan, EA Mead, W Lai… - Science, 2022 - science.org
The discovery of N6-methyldeoxyadenine (6mA) across eukaryotes led to a search for
additional epigenetic mechanisms. However, some studies have highlighted confounding …

[HTML][HTML] N6-deoxyadenosine methylation in mammalian mitochondrial DNA

Z Hao, T Wu, X Cui, P Zhu, C Tan, X Dou, KW Hsu… - Molecular cell, 2020 - cell.com
Summary N 6-Methyldeoxyadenosine (6mA) has recently been shown to exist and play
regulatory roles in eukaryotic genomic DNA (gDNA). However, the biological functions of …

[HTML][HTML] Hiding in plain sight: New virus genomes discovered via a systematic analysis of fungal public transcriptomes

KB Gilbert, EE Holcomb, RL Allscheid, JC Carrington - PLoS One, 2019 - journals.plos.org
The distribution and diversity of RNA viruses in fungi is incompletely understood due to the
often cryptic nature of mycoviral infections and the focused study of primarily pathogenic …

[HTML][HTML] Deciphering bacterial epigenomes using modern sequencing technologies

J Beaulaurier, EE Schadt, G Fang - Nature Reviews Genetics, 2019 - nature.com
Prokaryotic DNA contains three types of methylation: N6-methyladenine, N4-methylcytosine
and 5-methylcytosine. The lack of tools to analyse the frequency and distribution of …