[HTML][HTML] Mycobacterium tuberculosis drug-resistance testing: challenges, recent developments and perspectives

T Schön, P Miotto, CU Köser, M Viveiros… - Clinical Microbiology …, 2017 - Elsevier
Drug-resistance testing, or antimicrobial susceptibility testing (AST), is mandatory for
Mycobacterium tuberculosis in cases of failure on standard therapy. We reviewed the …

Emerging status of multidrug-resistant bacteria and fungi in the arabian peninsula

JF Borgio, AS Rasdan, B Sonbol, G Alhamid… - Biology, 2021 - mdpi.com
Simple Summary The incidence and developing status of multidrug-resistant bacteria and
fungi, as well as their related mortality, is reviewed by a systematic published literature …

[图书][B] Catalogue of mutations in Mycobacterium tuberculosis complex and their association with drug resistance

World Health Organization - 2023 - books.google.com
Page 1 Catalogue of mutations in Mycobacterium tuberculosis complex and their
association with drug resistance Second edition Page 2 Page 3 Catalogue of mutations in …

[HTML][HTML] Epidemiological cut-off values for a 96-well broth microdilution plate for high-throughput research antibiotic susceptibility testing of M. tuberculosis

CRyPTIC Consortium - European Respiratory Journal, 2022 - Eur Respiratory Soc
Drug susceptibility testing of M. tuberculosis is rooted in a binary susceptible/resistant
paradigm. While there are considerable advantages in measuring the minimum inhibitory …

First and second-line anti-tuberculosis drug-resistance patterns in pulmonary tuberculosis patients in Zambia

N Monde, M Munyeme, G Chongwe, JJ Wensman… - Antibiotics, 2023 - mdpi.com
Background: Drug-resistant tuberculosis has continued to be a serious global health threat
defined by complexity as well as higher morbidity and mortality wherever it occurs, Zambia …

Whole Genome Sequencing of Mycobacterium tuberculosis Clinical Isolates From India Reveals Genetic Heterogeneity and Region-Specific Variations That Might …

J Advani, R Verma, O Chatterjee, PK Pachouri… - Frontiers in …, 2019 - frontiersin.org
Whole genome sequencing (WGS) of Mycobacterium tuberculosis has been constructive in
understanding its evolution, genetic diversity and the mechanisms involved in drug …

Occurrence of disputed rpoB mutations among Mycobacterium tuberculosis isolates phenotypically susceptible to rifampicin in a country with a low incidence of …

NM Al-Mutairi, S Ahmad, E Mokaddas, HS Eldeen… - BMC infectious …, 2019 - Springer
Background Accurate drug susceptibility testing (DST) of Mycobacterium tuberculosis in
clinical specimens and culture isolates to first-line drugs is crucial for diagnosis and …

Clinical metagenomics for infectious corneal ulcers: Rags to riches?

L Ung, PJM Bispo, T Doan, RN Van Gelder… - The ocular …, 2020 - Elsevier
The emergence of clinical metagenomics as an unbiased, hypothesis-free approach to
diagnostic testing is set to fundamentally alter the way infectious diseases are detected …

Prediction of acquired antimicrobial resistance for multiple bacterial species using neural networks

D Aytan-Aktug, PTLC Clausen, V Bortolaia… - Msystems, 2020 - Am Soc Microbiol
Machine learning has proven to be a powerful method to predict antimicrobial resistance
(AMR) without using prior knowledge for selected bacterial species-antimicrobial …

Infection Inspection: using the power of citizen science for image-based prediction of antibiotic resistance in Escherichia coli treated with ciprofloxacin

A Farrar, C Feehily, P Turner, A Zagajewski… - Scientific Reports, 2024 - nature.com
Antibiotic resistance is an urgent global health challenge, necessitating rapid diagnostic
tools to combat its threat. This study uses citizen science and image feature analysis to …