Pregnancy involves a complex interplay between maternal neuroendocrine and
immunological systems in order to establish and sustain a growing fetus. It is thought that the …

The incidence of liver cancer is continuously rising where hepatocellular carcinoma (HCC)
remains the most common form of liver cancer accounting for approximately 80–90% of the …

Adoptive transfer of regulatory T cells (Tregs) prevents GVHD in experimental animals.
Because antigen activation drives Treg function, we measured the frequency, growth …

BACKGROUND & AIMS: T-cell immunoglobulin mucin (TIM) genes are expressed by T cells
and regulate host immunity and tolerance. CD4+ T cells mediate innate immunity-dominated …

The sex of a host affects the intensity, prevalence, and severity of helminth infection. In many
cases, one sex has been found to be more susceptible than the other, with the prevalence …

Sepsis is the leading cause of death for critically ill patients in recent years. Dendritic cells
(DCs) are important antigen‐presenting cells and play a key role in immune response by …

The T cell immunoglobulin and mucin domain‐containing molecules (TIM) protein family,
which is expressed by T cells, plays a crucial role in regulating host adaptive immunity and …

Delta-like ligand 4 (Dll4)–Notch signaling is essential for T cell development and alternative
thymic lineage decisions. How Dll4–Notch signaling affects pro-T cell fate and thymic …

CD4+ CD25+ Foxp3+ regulatory T cells (Tregs) restrict inflammatory responses to self and
nonself. Aberrant Treg activity is pathologic: Insufficient Treg activity is implicated in …

Dendritic cells (DCs) play an important role in anti-renal cell carcinoma (RCC) immunity. The
aim of the study was to investigate effect of mimic RCC microenvironment on phenotype and …