DNA methylation as a window into female reproductive aging

AK Knight, JB Spencer, AK Smith - Epigenomics, 2024 - Taylor & Francis
People with ovaries experience reproductive aging as their reproductive function and
system declines. This has significant implications for both fertility and long-term health, with …

[HTML][HTML] Oral Mycobiome Alterations in Postmenopausal Women: Links to Inflammation, Xerostomia, and Systemic Health

CF Bogdan-Andreescu, AM Bănățeanu, CC Albu… - Biomedicines, 2024 - mdpi.com
The oral mycobiome plays a critical role in maintaining oral and systemic health, with its
composition and function influenced by various physiological and environmental factors …

Immune cells are associated with mortality: the Health and Retirement Study

G Seshadri, S Vivek, A Prizment, EM Crimmins… - Frontiers in …, 2023 - frontiersin.org
Introduction Age-related immunosenescence is characterized by changes in immune cell
subsets and is associated with mortality. However, since immunosenescence is associated …

Markers and mechanisms of death in Drosophila

J Tower - Frontiers in Aging, 2023 - frontiersin.org
Parameters correlated with age and mortality in Drosophila melanogaster include
decreased negative geotaxis and centrophobism behaviors, decreased climbing and …

[HTML][HTML] Unraveling the interaction between inflammation and the cardiometabolic index in older men: A Pilot Study

RL Carvalho, TRP Brito, JB Amaral, FR Monteiro… - Nutrients, 2024 - mdpi.com
Both cardiometabolic and chronic inflammatory diseases pose a significant challenge to
global public health, particularly among older adults. Here, we investigated the interplay …

Overweight and obesity significantly increase colorectal cancer risk: a meta-analysis of 66 studies revealing a 25–57% elevation in risk

Z Ungvari, M Fekete, P Varga, A Lehoczki, JT Fekete… - GeroScience, 2024 - Springer
The incidence of colorectal cancer (CRC) has been steadily rising, and obesity has been
identified as a significant risk factor. Numerous studies suggest a strong correlation between …

Endothelial Colony-Forming Cells (ECFCs) in Cerebrovascular Aging: Focus on the Pathogenesis of Vascular Cognitive Impairment and Dementia (VCID), and …

S Negri, Z Reyff, E Troyano-Rodriguez, M Milan… - Ageing Research …, 2025 - Elsevier
Endothelial colony-forming cells (ECFCs), a unique endothelial progenitor subset, are
essential for vascular integrity and repair, providing significant regenerative potential …

U-shaped association of systemic immune-inflammation index levels with cancer-related and all-cause mortality in middle-aged and older individuals with frailty

Z Zheng, H Luo, Q Xue - Archives of Gerontology and Geriatrics, 2024 - Elsevier
Purpose Frailty is a state of heightened vulnerability to stress, whether from within the body
or external factors. We aim to assess the prognostic value of the Systemic Immune …

Analysis of COPD: Distinguishing Characteristics and Management of Smoking vs Never Smoking Patients

M Fekete, A Horvath, B Santa… - … Journal of Chronic …, 2024 - Taylor & Francis
Background Chronic obstructive pulmonary disease (COPD) is a significant public health
issue characterized by gradually worsening airflow limitation. It is a leading cause of …

The interplay of aging, adipose tissue, and COVID-19: a potent alliance with implications for health

J Quarleri, MV Delpino - GeroScience, 2024 - Springer
Obesity has emerged as a significant public health challenge. With the ongoing increase in
life expectancy, the prevalence of obesity is steadily growing, particularly among older age …