Chemokines and their receptors are involved in the pathogenesis of diseases ranging from
asthma to AIDS. Chemokine receptors are G-protein-coupled serpentine receptors that …

Asthma and asthma-related traits are complex diseases with strong genetic and
environmental components. Rapid progress in asthma genetics has led to the identification …

A genetic basis for atopic dermatitis (AD) has long been recognized. Historic documents
allude to family history of disease as a risk factor. Before characterization of the human …

Asthma is a triad of intermittent airway obstruction, bronchial smooth muscle cell
hyperreactivity to bronchoconstrictors, and chronic bronchial inflammation. From an …

OBJECTIVE. The goal was to develop multivariate logistic regression models for the
outcome of bronchopulmonary dysplasia and/or death at postmenstrual age of 36 weeks by …

Background Chronic skin inflammation in atopic dermatitis (AD) is associated with elevated
expression of proinflammatory genes and activation of innate immune responses in …

Background: Atopic dermatitis (AD) and psoriasis are genetically determined inflammatory
skin disorders. Keratinocytes actively participate in cutaneous inflammatory responses by …

Atopic dermatitis (AD) is a common, fluctuating skin disease that is often associated with
atopic conditions such as asthma and IgE-mediated food allergy and whose skin lesions are …

Atopic dermatitis (AD) is a multifactorial inflammatory skin disease resulting from interactions
between genetic susceptibility and environmental factors. The pathogenesis of AD is poorly …

The asthmatic response is characterized by elevated production of IgE, cytokines,
chemokines, mucus hypersecretion, airway obstruction, eosinophilia, and enhanced airway …