Beyond gel electrophoresis: Microfluidic separations, fluorescence burst analysis, and DNA stretching

KD Dorfman, SB King, DW Olson, JDP Thomas… - Chemical …, 2013 - ACS Publications
This Review addresses methods for obtaining sequence information directly from
unamplified genomic length DNA. Our generic starting point is a large piece of DNA that …

DNA in nanochannels: theory and applications

K Frykholm, V Müller, KK Sriram… - Quarterly Reviews of …, 2022 - cambridge.org
Nanofluidic structures have over the last two decades emerged as a powerful platform for
detailed analysis of DNA on the kilobase pair length scale. When DNA is confined to a …

Fabrication of nanofluidic biochips with nanochannels for applications in DNA analysis

D Xia, J Yan, S Hou - Small, 2012 - Wiley Online Library
With the development of nanotechnology, great progress has been made in the fabrication
of nanochannels. Nanofluidic biochips based on nanochannel structures allow biomolecule …

Electrokinetically-driven transport of DNA through focused ion beam milled nanofluidic channels

LD Menard, JM Ramsey - Analytical chemistry, 2013 - ACS Publications
The electrophoretically driven transport of double-stranded λ-phage DNA through focused
ion beam (FIB) milled nanochannels is described. Nanochannels were fabricated having …

Unconventional micro-/nanofabrication technologies for hybrid-scale lab-on-a-chip

D Ha, J Hong, H Shin, T Kim - Lab on a Chip, 2016 - pubs.rsc.org
Micro-/nanofabrication-based lab-on-a-chip (LOC) technologies have recently been
substantially advanced and have become widely used in various inter-/multidisciplinary …

Single digit nanofabrication by step-and-repeat nanoimprint lithography

C Peroz, S Dhuey, M Cornet, M Vogler… - …, 2011 - iopscience.iop.org
A novel strategy for fabricating nanoimprint templates with sub-10 nm patterns is
demonstrated by combining electron beam lithography and atomic layer deposition …

Two dimensional PMMA nanofluidic device fabricated by hot embossing and oxygen plasma assisted thermal bonding methods

Z Yin, L Sun, H Zou, E Cheng - Nanotechnology, 2015 - iopscience.iop.org
A method for obtaining a low-cost and high-replication precision two-dimensional (2D)
nanofluidic device with a polymethyl methacrylate (PMMA) sheet is proposed. To improve …

A non-enzymatic uric acid sensor utilizing ion channels in the barrier layer of a porous anodic alumina membrane

T Su, L He, R Mo, C Zhou, Z Wang, Y Wang… - Electrochemistry …, 2018 - Elsevier
Porous anodic alumina (PAA) membranes have attracted considerable interest in biosensor
research because they are simple to prepare and the size of the nanochannels can be …

Fabrication of two dimensional polyethylene terephthalate nanofluidic chip using hot embossing and thermal bonding technique

Z Yin, E Cheng, H Zou, L Chen, S Xu - Biomicrofluidics, 2014 - pubs.aip.org
We present in this paper a method for obtaining a low cost and high replication precision 2D
(two dimensional) nanofluidic chip with a PET (polyethylene terephthalate) sheet, which …

Label-free electrical quantification of amplified nucleic acids through nanofluidic diodes

Y Liu, L Yobas - Biosensors and Bioelectronics, 2013 - Elsevier
A label-free method of quantifying nucleic acids in polymerase chain reaction (PCR) is
described and could be the basis for miniaturized devices that can amplify and detect target …