Lipids constitute the bulk of the dry mass of the brain and have been associated with healthy
function as well as the most common pathological conditions of the brain. Demographic …

Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …

Abstract In 1972 the Fluid—Mosaic Membrane Model of membrane structure was proposed
based on thermodynamic principals of organization of membrane lipids and proteins and …

Lipid-mediated signalling regulates a plethora of physiological processes, including crucial
aspects of brain function. In addition, dysregulation of lipid pathways has been implicated in …

Sphingomyelin (SM) is a dominant sphingolipid in membranes of mammalian cells and this
lipid class is specifically enriched in the plasma membrane, the endocytic recycling …

The dynamics of constituents and the surface response of cellular membranes—also in
connection to the binding of various particles and macromolecules to the membrane—are …

Plasma membrane compartmentalization spatiotemporally regulates cell-autonomous
immune signaling in animal cells. To elucidate immediate early protein dynamics at the plant …

Since the first X-ray structure of Cry3Aa was revealed in 1991, numerous structures of B.
thuringiensis toxins have been determined and published. In recent years, functional studies …

The plasma membrane is made up of lipids and proteins, and serves as an active interface
between the cell and its environment. Many plasma-membrane proteins are laterally …

Lipid rafts, also known as microdomains, are important components of cell membranes and
are enriched in cholesterol, glycophospholipids and receptors. They are involved in various …