Increasing global energy demand and environmental concerns associated with petroleum
have raised interest in biofuels for reducing dependency on crude oil and promote carbon …

Background Analysis of the glutamine metabolic pathway has taken a special place in
metabolomics research in recent years, given its important role in cell biosynthesis and …

Abstract Roger WH Sargent (1926–2018) was an unprecedented pioneer who foresaw the
role that mathematical and computational tools would have in chemical engineering. His …

Radioactive and stable isotopes have been applied for decades to elucidate metabolic
pathways and quantify carbon flow in cellular systems using mass and isotope balancing …

Evidence indicates that metabolic reprogramming characterized by the changes in cellular
metabolic patterns contributes to the pathogenesis of pulmonary fibrosis (PF). It is …

Chinese hamster ovary (CHO) cells have been widely used for producing many recombinant
therapeutic proteins. Constraint‐based modeling, such as flux balance analysis (FBA) and …

The study of intracellular metabolic fluxes and inter-species metabolite exchange for
microbial communities is of crucial importance to understand and predict their behaviour …

Currently, industrial production of l-threonine (Thr) is based on direct fermentation with
microorganisms such as Escherichia coli, which has the characteristics of low cost and high …

In the present study, the effects of individual as well as multiple genes of pentose phosphate
pathway (PPP) on human interferon gamma (hIFN-γ) production were analyzed. With …

Mycoplasma bovis is an economically important pathogen of the cattle industry worldwide,
and there is an urgent need for a more effective vaccine to control the diseases caused by …