Platelets are most important in providing cellular hemostasis but also take part in
inflammation and immune processes. Increased platelet size has been regarded as a …

Genetic defects of platelets constitute rare diseases that include bleeding syndromes of
autosomal dominant, recessive or X‐linked inheritance. They affect platelet production …

In platelets, splicing and translation occur in the absence of a nucleus. However, the integrity
and stability of mRNAs derived from megakaryocyte progenitor cells remain poorly …

Introduction Blood production in humans culminates in the daily release of around 1011
cells into the circulation, mainly platelets and red blood cells. All blood cells originate from a …

Genetic variation at the chromosome 9p21 risk locus promotes cardiovascular disease;
however, it is unclear how or which proteins encoded at this locus contribute to disease. We …

Platelet production, maintenance, and clearance are tightly controlled processes indicative
of platelets' important roles in hemostasis and thrombosis. Platelets are common targets for …

Platelets are anucleate cytoplasmic fragments that lack genomic DNA, but continue to
synthesize protein using a pool of messenger RNAs (mRNAs), ribosomes, and regulatory …

The ins and outs of endocytic trafficking in platelet functi... : Current Opinion in Hematology
The ins and outs of endocytic trafficking in platelet functions : Current Opinion in …

Coronary heart disease (CHD) is the leading cause of mortality in both developed and
developing countries worldwide. Genome-wide association studies (GWAS) have now …

Genome-wide association studies have shown that the far majority of disease-associated
variants reside in the non-coding regions of the genome, suggesting that gene regulatory …