The human microbiome and cancer: a diagnostic and therapeutic perspective

S Kandalai, H Li, N Zhang, H Peng… - Cancer Biology & …, 2023 - Taylor & Francis
Recent evidence has shown that the human microbiome is associated with various
diseases, including cancer. The salivary microbiome, fecal microbiome, and circulating …

Broadening oncological boundaries: the intratumoral microbiota

YQ Lu, H Qiao, XR Tan, N Liu - Trends in Microbiology, 2024 - cell.com
The microbiota of solid tumors was identified> 100 years ago; however, heterogeneous
composition and diversity have been revealed only recently. Growing evidence has …

Major data analysis errors invalidate cancer microbiome findings

A Gihawi, Y Ge, J Lu, D Puiu, A Xu, CS Cooper… - MBio, 2023 - Am Soc Microbiol
We re-analyzed the data from a recent large-scale study that reported strong correlations
between DNA signatures of microbial organisms and 33 different cancer types and that …

Pan-cancer analyses reveal the stratification of patient prognosis by viral composition in tumor tissues

Y Zhang, L Ji, H Wen, Y Chu, W Xing, G Tian… - Computers in biology …, 2023 - Elsevier
The associations between cancer and bacteria/fungi have been extensively studied, but the
implications of cancer-associated viruses have not been thoroughly examined. In this study …

Antibacterial tellurium-containing polycarbonate drug carriers to eliminate intratumor bacteria for synergetic chemotherapy against colorectal cancer

J Hu, S Ran, Z Huang, Y Liu, H Hu, Y Zhou, X Ding… - Acta Biomaterialia, 2024 - Elsevier
Intratumor microbes have attracted great attention in cancer research due to its influence on
the tumorigenesis, progression and metastasis of cancer. However, the therapeutic …

[HTML][HTML] Pan-cancer atlas of tumor-resident microbiome, immunity and prognosis

D Sheng, C Jin, K Yue, M Yue, Y Liang, X Xue, P Li… - Cancer Letters, 2024 - Elsevier
The existence of microbiome in human tumors has been determined widely, but evaluating
the contribution of intratumoral bacteria and fungi to tumor immunity and prognosis from a …

Identification of intratumor bacteria-associated prognostic risk score in adrenocortical carcinoma

L Tan, D Zhang, Y Li, Y Li, T Guo, Y Sun… - Microbiology …, 2024 - Am Soc Microbiol
ABSTRACT A landmark study by Poore et al. showed intratumor bacteria (ITBs) playing a
critical role in most cancers by reproduction of The Cancer Genome Atlas (TCGA) …

Comprehensive analysis of microbial content in whole-genome sequencing samples from The Cancer Genome Atlas project

Y Ge, J Lu, D Puiu, M Revsine, SL Salzberg - bioRxiv, 2024 - biorxiv.org
In recent years, a growing number of publications have reported the presence of microbial
species in human tumors and of mixtures of microbes that appear to be highly specific to …