A novel diabetes typology: towards precision diabetology from pathogenesis to treatment
C Herder, M Roden - Diabetologia, 2022 - Springer
The current classification of diabetes, based on hyperglycaemia, islet-directed antibodies
and some insufficiently defined clinical features, does not reflect differences in aetiological …
and some insufficiently defined clinical features, does not reflect differences in aetiological …
Precision subclassification of type 2 diabetes: a systematic review
Background Heterogeneity in type 2 diabetes presentation and progression suggests that
precision medicine interventions could improve clinical outcomes. We undertook a …
precision medicine interventions could improve clinical outcomes. We undertook a …
Heterogeneity in phenotype, disease progression and drug response in type 2 diabetes
ATN Nair, A Wesolowska-Andersen, C Brorsson… - Nature Medicine, 2022 - nature.com
Abstract Type 2 diabetes (T2D) is a complex chronic disease characterized by considerable
phenotypic heterogeneity. In this study, we applied a reverse graph embedding method to …
phenotypic heterogeneity. In this study, we applied a reverse graph embedding method to …
Phenotypic and genetic classification of diabetes
The historical subclassification of diabetes into predominantly types 1 and 2 is well
appreciated to inadequately capture the heterogeneity seen in patient presentations …
appreciated to inadequately capture the heterogeneity seen in patient presentations …
[HTML][HTML] University students' participation in outdoor recreation and the perceived well-being effects of nature
R Puhakka - Journal of outdoor recreation and tourism, 2021 - Elsevier
It is increasingly recognized that interacting with nature promotes well-being and health for
both adults and children. Less is known about the role of nature in people's everyday lives …
both adults and children. Less is known about the role of nature in people's everyday lives …
Integrating polygenic risk scores in the prediction of type 2 diabetes risk and subtypes in British Pakistanis and Bangladeshis: A population-based cohort study
Background Type 2 diabetes (T2D) is highly prevalent in British South Asians, yet they are
underrepresented in research. Genes & Health (G&H) is a large, population study of British …
underrepresented in research. Genes & Health (G&H) is a large, population study of British …
Type 2 diabetes classification: a data-driven cluster study of the Danish Centre for Strategic Research in Type 2 Diabetes (DD2) cohort
DH Christensen, SK Nicolaisen, E Ahlqvist… - BMJ Open Diabetes …, 2022 - drc.bmj.com
Introduction A Swedish data-driven cluster study identified four distinct type 2 diabetes (T2D)
clusters, based on age at diagnosis, body mass index (BMI), hemoglobin A1c (HbA1c) level …
clusters, based on age at diagnosis, body mass index (BMI), hemoglobin A1c (HbA1c) level …
100 YEARS OF INSULIN: Towards improved precision and a new classification of diabetes mellitus
Type 2 diabetes (T2D) is one of the fastest increasing diseases worldwide. Although it is
defined by a single metabolite, glucose, it is increasingly recognized as a highly …
defined by a single metabolite, glucose, it is increasingly recognized as a highly …
Metabolic and proteomic signatures of type 2 diabetes subtypes in an Arab population
Abstract Type 2 diabetes (T2D) has a heterogeneous etiology influencing its progression,
treatment, and complications. A data driven cluster analysis in European individuals with …
treatment, and complications. A data driven cluster analysis in European individuals with …
Altered blood gene expression in the obesity-related type 2 diabetes cluster may be causally involved in lipid metabolism: a Mendelian randomisation study
Aims/hypothesis The aim of this study was to identify differentially expressed long non-
coding RNAs (lncRNAs) and mRNAs in whole blood of people with type 2 diabetes across …
coding RNAs (lncRNAs) and mRNAs in whole blood of people with type 2 diabetes across …