Spina bifida

AJ Copp, NS Adzick, LS Chitty, JM Fletcher… - Nature reviews Disease …, 2015 - nature.com
Spina bifida is a birth defect in which the vertebral column is open, often with spinal cord
involvement. The most clinically significant subtype is myelomeningocele (open spina …

[HTML][HTML] Risks of specific congenital anomalies in offspring of women with diabetes: A systematic review and meta-analysis of population-based studies including over …

TN Zhang, XM Huang, XY Zhao, W Wang, R Wen… - PLoS …, 2022 - journals.plos.org
Background Pre-gestational diabetes mellitus (PGDM) has been known to be a risk factor for
congenital heart defects (CHDs) for decades. However, the associations between maternal …

Association of maternal prepregnancy diabetes and gestational diabetes mellitus with congenital anomalies of the newborn

Y Wu, B Liu, Y Sun, Y Du, MK Santillan… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE To examine the association of maternal prepregnancy diabetes, gestational
diabetes mellitus (GDM), and 12 subtypes of congenital anomalies of the newborn …

Maternal overweight and obesity and the risk of congenital anomalies: a systematic review and meta-analysis

KJ Stothard, PWG Tennant, R Bell, J Rankin - Jama, 2009 - jamanetwork.com
Context Evidence suggests an association between maternal obesity and some congenital
anomalies. Objective To assess current evidence of the association between maternal …

Noninherited risk factors and congenital cardiovascular defects: current knowledge: a scientific statement from the American Heart Association Council on …

KJ Jenkins, A Correa, JA Feinstein, L Botto, AE Britt… - Circulation, 2007 - Am Heart Assoc
Prevention of congenital cardiovascular defects has been hampered by a lack of information
about modifiable risk factors for abnormalities in cardiac development. Over the past …

Diabetes mellitus and birth defects

A Correa, SM Gilboa, LM Besser, LD Botto… - American journal of …, 2008 - Elsevier
OBJECTIVE: The purpose of this study was to examine associations between diabetes
mellitus and 39 birth defects. STUDY DESIGN: This was a multicenter case-control study of …

Neural-tube defects

LD Botto, CA Moore, MJ Khoury… - New England journal of …, 1999 - Mass Medical Soc
Each year spina bifida and anencephaly, the two most common forms of neural-tube defects,
occur in 1 in 1000 pregnancies in the United States1 and an estimated 300,000 or more …

Maternal obesity and risk for birth defects

ML Watkins, SA Rasmussen, MA Honein, LD Botto… - …, 2003 - publications.aap.org
Objective. Several studies have shown an increased risk for neural tube defects associated
with prepregnancy maternal obesity. Because few recent studies have examined the relation …

Maternal treatment with opioid analgesics and risk for birth defects

CS Broussard, SA Rasmussen, J Reefhuis… - American journal of …, 2011 - Elsevier
OBJECTIVE: We examined whether maternal opioid treatment between 1 month before
pregnancy and the first trimester was associated with birth defects. STUDY DESIGN: The …

[HTML][HTML] Vacterl/vater association

BD Solomon - Orphanet journal of rare diseases, 2011 - Springer
VACTERL/VATER association is typically defined by the presence of at least three of the
following congenital malformations: vertebral defects, anal atresia, cardiac defects, tracheo …