Production, function, and applications of the sesquiterpenes valencene and nootkatone: A comprehensive review

LL Zhang, Y Chen, ZJ Li, G Fan, X Li - Journal of Agricultural and …, 2022 - ACS Publications
Valencene and nootkatone, two sesquiterpenes, extracted from natural sources, have great
market potential with diverse applications. This paper aims to comprehensively review the …

Therapeutic potential of AMPK signaling targeting in lung cancer: advances, challenges and future prospects

M Ashrafizadeh, S Mirzaei, K Hushmandi… - Life sciences, 2021 - Elsevier
Lung cancer (LC) is a leading cause of death worldwide with high mortality and morbidity. A
wide variety of risk factors are considered for LC development such as smoking, air pollution …

[HTML][HTML] Sesquiterpene nootkatone counteracted the melamine-induced neurotoxicity via repressing of oxidative stress, inflammatory, and apoptotic trajectories

OA Habotta, A Abdeen, AA El-Hanafy, N Yassin… - Biomedicine & …, 2023 - Elsevier
Melamine (ML), a chemical substance of high nitrogen content, is used as a food adulterant.
Former evidences implied that ML could induce a variety of toxic effects including …

Nootkatone attenuates myocardial oxidative damage, inflammation, and apoptosis in isoproterenol-induced myocardial infarction in rats

MFN Meeran, S Azimullah, E Adeghate, S Ojha - Phytomedicine, 2021 - Elsevier
Background Myocardial infarction (MI) is a lethal manifestation of cardiovascular diseases.
Oxidative stress, inflammation, and subsequent cell death are known to play crucial roles in …

Ginsenoside Rh2 ameliorates lipopolysaccharide-induced acute lung injury by regulating the TLR4/PI3K/Akt/mTOR, Raf-1/MEK/ERK, and Keap1/Nrf2/HO-1 signaling …

YH Hsieh, JS Deng, YS Chang, GJ Huang - Nutrients, 2018 - mdpi.com
The anti-inflammatory effect of ginsenoside Rh2 (GRh2) has labeled it as one of the most
important ginsenosides. The purpose of this study was to identify the anti-inflammatory and …

Impact of Lactobacillus plantarum 423 fermentation on the antioxidant activity and flavor properties of rice bran and wheat bran

M Wang, M Lei, N Samina, LL Chen, CL Liu, TT Yin… - Food Chemistry, 2020 - Elsevier
Rice bran (RB) and wheat bran (WB) fermented with L. plantarum 423 had enhanced odor
intensity, especially for sulfides and aromatics. The hydroxyl radical-scavenging activity …

Catalpol attenuates oxidative stress and inflammation via mechanisms involving sirtuin-1 activation and NF-κB inhibition in experimentally-induced chronic kidney …

NE Zaaba, S Al-Salam, S Beegam, O Elzaki, J Yasin… - Nutrients, 2023 - mdpi.com
Chronic kidney disease (CKD) is a stealthy disease, and its development is linked to
mechanisms including inflammation and oxidative stress. Catalpol (CAT), an iridoid …

Nootkatone supplementation ameliorates carbon tetrachloride-induced acute liver injury via the inhibition of oxidative stress, NF-κB pathways, and the activation of …

C Dai, X Zhang, J Lin, J Shen - Antioxidants, 2023 - mdpi.com
Acute liver injury is a type of liver diseases, and it has raised concerns worldwide due to the
lack of effective therapies. The aim of this study is to investigate the protective effects of …

NQO1 mediates the anti-inflammatory effects of nootkatone in lipopolysaccharide-induced neuroinflammation by modulating the AMPK signaling pathway

JE Park, JS Park, YH Leem, DY Kim, HS Kim - Free Radical Biology and …, 2021 - Elsevier
Neuroinflammation and oxidative stress play key roles in the progression of
neurodegenerative diseases. Thus, the use of potent anti-inflammatory/antioxidant agents …

Diesel soot combustion over ceria catalyst: Evolution of functional groups on soot surfaces

J Wei, C Fan, Y Zhuang, Z Fu, Z Guan, H Li, D Li… - Fuel, 2023 - Elsevier
The use of ceria catalyst is a common way to promote the soot combustion during DPF
regeneration, due to the superior capability to store and release oxygen. In this work, the …