Structural and functional integrity of the cerebral vasculature ensures proper brain
development and function, as well as healthy aging. The inability of the brain to store energy …

Background/Objectives: Retinopathy of prematurity (ROP) is a severe condition primarily
affecting premature infants with a gestational age (GA) of 30 weeks or less and a birth …

Background Tissue stem cells are confined within a special microenvironment called niche.
Stem cells in such a niche are supplied with nutrients and contacted by other cells to …

The inner ear has a rich population of pericytes, a multi-functional mural cell essential for
sensory hair cell heath and normal hearing. However, the mechanics of how pericytes …

The complex interplay between vascular signaling and neurogenesis in the adult brain
remains a subject of intense research. By exploiting the unique advantages of the zebrafish …

Amyloid Precursor Protein (APP) and its cleavage processes have been widely investigated
in the past, in particular in the context of Alzheimer's Disease (AD). Evidence of an increased …

Human life expectancy has been significantly extended, which poses major challenges to
our healthcare and social systems. Aging-associated cognitive impairment is attributed to …

Background Current evidence suggests that microvessel disease is involved in Alzheimer's
disease (AD). Cerebrovascular disease correlates with cardiovascular disease and is …

Pre-eclampsia (PE) is a hypertensive disorder of pregnancy which is associated with
increased risk of neurodevelopmental disorders in exposed offspring. The …

Many sex differences in brain and behavior are established developmentally by the
opposing processes of feminization and masculinization, which manifest following …