The shortening of human telomeres has two opposing effects during cancer development.
On the one hand, telomere shortening can exert a tumour-suppressive effect through the …

Despite much recent progress, prostate cancer continues to represent a major cause of
cancer-related mortality and morbidity in men. Since early studies on the role of the …

Correspondence to S. Bacchetti. research in this field may render the information rapidly
outdated, we hope that the present survey of over 3500 tumour and control samples will aid …

This 2004 volume in the World Health Organization series on histologic and genetic typing
of human tumors covers tumors of the kidney, urinary system, prostate, testis and …

Prostate cancer has the highest prevalence of any nonskin cancer in the human body, with
similar likelihood of neoplastic foci found within the prostates of men around the world …

Prostate cancer afflicts one man in nine over the age of 65 and represents the most
frequently diagnosed cancer in American men (Coffey 1993). Early detection through serum …

Background Telomeres play a key role in the maintenance of chromosome integrity and
stability, and telomere shortening is involved in initiation and progression of malignancies. A …

We identified DD3 PCA3 as one of the most prostate cancer-specific genes at present (MJ
Bussemakers et al. Cancer Res., 59: 5975–5979, 1999). Consequently, DD3 PCA3 is an …

Prostate cancer is the most commonly diagnosed male malignancy. Despite compelling
epidemiology, there are no definitive aetiological clues linking development to frequency …

This review focuses on new findings and controversial issues in the pathology and
molecular biology of adenocarcinoma of the prostate. Since management of high-grade …