The heart failure syndrome has first been described as an emerging epidemic about 25
years ago. Today, because of a growing and ageing population, the total number of heart …

Heart failure patients are classified by ejection fraction (EF) into distinct groups: heart failure
with preserved ejection fraction (HFpEF) or heart failure with reduced ejection fraction …

Background: Heart failure (HF) with preserved ejection fraction (HFpEF) is a heterogeneous
syndrome. Phenotyping patients into pathophysiologically homogeneous groups may …

Background—Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone
Antagonist (TOPCAT) patients with heart failure and preserved left ventricular ejection …

Aims A substantial proportion of patients with heart failure have preserved left ventricular
ejection fraction (HF-PEF). Previous studies have reported mixed results whether survival is …

ESC Guidelines 2389 disclosure forms are kept on file at the European Heart House,
headquarters of the ESC. Any changes in conflict of interest that arise during the writing …

Background—When advanced, heart failure with preserved ejection fraction (HFpEF) is
readily apparent. However, diagnosis of earlier disease may be challenging because …

Heart failure with preserved ejection fraction (HFPEF) is increasingly recognized as a major
public health problem worldwide. Significant advances have been made in our …

Background Approximately 50% of patients with heart failure have a left ventricular ejection
fraction of at least 45%, but no therapies have been shown to improve the outcome of these …

Background The prevalence of heart failure with preserved ejection fraction may be
changing as a result of changes in population demographics and in the prevalence and …