[HTML][HTML] Role of stromal paracrine signals in proliferative diseases of the aging human prostate

K Ishii, S Takahashi, Y Sugimura… - Journal of Clinical …, 2018 - mdpi.com
Androgens are essential for the development, differentiation, growth, and function of the
prostate through epithelial–stromal interactions. However, androgen concentrations in the …

Stromal cell interplay in prostate development, physiology, and pathological conditions

BDA Sanches, JS Maldarine, PSL Vilamaior… - The …, 2021 - Wiley Online Library
Advances in prostatic stroma studies over the past few decades have demonstrated that the
stroma not only supports and nourishes the gland's secretory epithelium but also …

Testosterone Stimulates Growth and Secretory Activity of the Female Prostate in the Adult Gerbil (Meriones unguiculatus)

FCA Santos, RP Leite, AMG Custódio… - Biology of …, 2006 - academic.oup.com
The prostate of the female gerbil (Meriones unguiculatus) is similar to the human female
prostate (Skene gland) and, despite its reduced size, it is functional and shows secretory …

[HTML][HTML] Gene expression profile of stromal factors in cancer-associated fibroblasts from prostate cancer

N Eiro, JM Fernández-Gómez… - Diagnostics, 2022 - mdpi.com
Recent investigations point at the stromal microenvironment to assess additional diagnostic
information and provide new therapeutic targets in cancer. The aim of the study was to …

Prostatic morphological changes throughout life: Cytochemistry as a tool to reveal tissue aging markers

LHA Guerra, SGP Campos, SR Taboga… - Microscopy …, 2024 - Wiley Online Library
The prostate undergoes normal or pathological morphological changes throughout life. An
understanding of these changes is fundamental for the comprehension of aging‐related …

Key participants of the tumor microenvironment of the prostate: An approach of the structural dynamic of cellular elements and extracellular matrix components during …

BF Goncalves, SGP de Campos, CFP Costa… - Acta histochemica, 2015 - Elsevier
Cancer is a multistep process that begins with the transformation of normal epithelial cells
and continues with tumor growth, stromal invasion and metastasis. The remodeling of the …

[HTML][HTML] The prostate after castration and hormone replacement in a rat model: structural and ultrastructural analysis

B Felix-Patrício, AF Miranda, JL Medeiros Jr… - International braz j …, 2017 - SciELO Brasil
Purpose: To evaluate if late hormonal replacement is able to recover the prostatic tissue
modified by androgenic deprivation. Materials and Methods: 24 rats were assigned into a …

[HTML][HTML] Prostate telocytes change their phenotype in response to castration or testosterone replacement

SL Felisbino, BDA Sanches, FK Delella, WR Scarano… - Scientific reports, 2019 - nature.com
Telocytes are CD34-positive cells with a fusiform cell body and long, thin cytoplasmic
projections called telopodes. These cells were detected in the stroma of various organs …

Oestrogen supplementation following castration promotes stromal remodelling and histopathological alterations in the Mongolian gerbil ventral prostate

WR Scarano, DE De Sousa… - International Journal …, 2008 - Wiley Online Library
The effect of oestradiol on the intact and castrated adult gerbil prostate was evaluated by
focussing on stromal and epithelial disorders, and hormonal receptor immunoreactivity. The …

Hormonal oscillations during the estrous cycle influence the morphophysiology of the gerbil (Meriones unguiculatus) female prostate (skene paraurethral glands)

RA Fochi, APS Perez, CV Bianchi… - Biology of …, 2008 - academic.oup.com
The hormonal oscillations that occur during the female reproductive cycle influence the
morphophysiology of several organs of the reproductive system. The female prostate is a …