[HTML][HTML] A peripheral blood mononuclear cell-based in vitro model: A tool to explore indoleamine 2, 3-dioxygenase-1 (IDO1)

M Gonçalves, A Furgiuele, E Rasini, M Legnaro… - European Journal of …, 2024 - Elsevier
Background Proinflammatory cytokines powerfully induce the rate-limiting enzyme
indoleamine 2, 3-dioxygenase-1 (IDO-1) in dendritic cells (DCs) and monocytes, it converts …

Single-cell multi-omics analysis reveals IFN-driven alterations in T lymphocytes and natural killer cells in systemic lupus erythematosus

D Trzupek, M Lee, F Hamey, LS Wicker… - Wellcome Open …, 2022 - pmc.ncbi.nlm.nih.gov
Background: The characterisation of the peripheral immune system in the autoimmune
disease systemic lupus erythematosus (SLE) at the single-cell level has been limited by the …