Despite the clinically recognized association between endometriosis and infertility, the
mechanisms implicated in endometriosis-associated infertility are not fully understood …

In the healthy endometrium, progesterone and estrogen signaling coordinate in a tightly
regulated, dynamic interplay to drive a normal menstrual cycle and promote an embryo …

Estrogen and progesterone and their signaling mechanisms are tightly regulated to maintain
a normal menstrual cycle and to support a successful pregnancy. The imbalance of estrogen …

BACKGROUND The reproductive impact of adenomyosis and endometriosis is widely
researched but the extent of these impacts remains elusive. It has been demonstrated that …

Originally described over three hundred years ago, endometriosis is classically defined by
the presence of endometrial glands and stroma in extrauterine locations. Endometriosis is …

Endometriosis has been estimated to affect up to 10% to 15% of reproductive-age women. 1
The association between endometriosis and infertility is well supported throughout the …

Embryo implantation involves the intimate interaction between an implantation-competent
blastocyst and a receptive uterus, which occurs in a limited time period known as the …

Women with endometriosis typically present with pelvic pain, infertility, or an adnexal mass,
and may require surgery. Treatment of endometriosis in the setting of infertility raises a …

In murine and human pregnancies, embryos implant by attaching to the luminal epithelium
and invading into the stroma of the endometrium. Under the influence of the steroid …

HOX genes convey positional identity that leads to the proper partitioning and adult identity
of the female reproductive track. Abnormalities in reproductive tract development can be …