The heart is a highly structured organ consisting of different cell types, including myocytes,
endothelial cells, fibroblasts, stem cells, and inflammatory cells. This pluricellularity provides …

Heart attack remains the leading cause of death in both men and women worldwide. Stem
cell-based therapies, including the use of engineered cardiac tissues, have the potential to …

The ability of human pluripotent stem cells (hPSCs) to differentiate into any cell type of the
three germ layers makes them a very promising cell source for multiple purposes, including …

H9c2 myoblasts are a cell line derived from embryonic rat heart tissue and demonstrate the
ability to differentiate to cardiac myotubes upon reduction of the serum concentration (from …

Human embryonic stem cells have emerged as the prototypical source from which
cardiomyocytes can be derived for use in drug discovery and cell therapy. However, such …

Conventional fertility preservation methods such as oocyte or embryo cryopreservation are
currently insufficient to treat including those patients with prepubertal cancer and premature …

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have emerged
as a powerful platform for in vitro modelling of cardiac diseases, safety pharmacology and …

Since the first description of human induced pluripotent stem cell-derived cardiomyocytes
(hiPSC-CMs), these cells have garnered tremendous interest for their potential use in patient …

Background: The development and use of human embryonic stem cells (hESCs) in
regenerative medicine have been revolutionary, offering significant advancements in …

With the intent to achieve the best modalities for myocardial cell therapy, different cell types
are being evaluated as potent sources for differentiation into cardiomyocytes. Embryonic …