Tetrahydrocannabinol (THC) has been the primary focus of cannabis research since 1964,
when Raphael Mechoulam isolated and synthesized it. More recently, the synergistic …

Odor signals received by odorant receptors (ORs) expressed by olfactory sensory neurons
(OSNs) in the olfactory epithelium (OE) are represented as an odor map in the olfactory bulb …

Drosophila olfactory sensory neurons (OSNs) each express two odorant receptors (ORs): a
divergent member of the OR family and the highly conserved, broadly expressed receptor …

Gene positioning and regulation of nuclear architecture are thought to influence gene
expression. Here, we show that, in mouse olfactory neurons, silent olfactory receptor (OR) …

Transport of G protein-coupled receptors (GPCRs) to the cell surface membrane is critical in
order for the receptors to recognize their ligands. However, mammalian GPCR odorant …

The expression of a single odorant receptor (OR) gene from a large gene family in individual
sensory neurons is an essential feature of the organization and function of the olfactory …

Constitutive heterochromatin is traditionally viewed as the static form of heterochromatin that
silences pericentromeric and telomeric repeats in a cell cycle-and differentiation …

The transcriptional activation of one out of∼ 2800 olfactory receptor (OR) alleles is a poorly
understood process. Here, we identify a plethora of putative OR enhancers and study their in …

Olfaction, the sense of smell detects and discriminate odors as well as social cues which
influence our innate responses. The olfactory system in human beings is found to be weak …

Olfactory sensory neurons (OSNs) convert the stochastic choice of one of> 1,000 olfactory
receptor (OR) genes into precise and stereotyped axon targeting of OR-specific glomeruli in …