Obesity, kidney dysfunction and hypertension: mechanistic links

JE Hall, JM do Carmo, AA da Silva, Z Wang… - Nature reviews …, 2019 - nature.com
Excessive adiposity raises blood pressure and accounts for 65–75% of primary
hypertension, which is a major driver of cardiovascular and kidney diseases. In obesity …

Obesity-induced hypertension: interaction of neurohumoral and renal mechanisms

JE Hall, JM do Carmo, AA da Silva, Z Wang… - Circulation …, 2015 - Am Heart Assoc
Excess weight gain, especially when associated with increased visceral adiposity, is a major
cause of hypertension, accounting for 65% to 75% of the risk for human primary (essential) …

2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of …

G Mancia, R Kreutz, M Brunström, M Burnier… - Journal of …, 2023 - journals.lww.com
Document Reviewers: Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici
(Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luıs Bronze (Portugal), John …

The sympathetic nervous system alterations in human hypertension

G Grassi, A Mark, M Esler - Circulation research, 2015 - Am Heart Assoc
Several articles have dealt with the importance and mechanisms of the sympathetic nervous
system alterations in experimental animal models of hypertension. This review addresses …

The autonomic nervous system and hypertension

G Mancia, G Grassi - Circulation research, 2014 - Am Heart Assoc
Physiological studies have long documented the key role played by the autonomic nervous
system in modulating cardiovascular functions and in controlling blood pressure values …

New approaches in the treatment of hypertension

S Oparil, RE Schmieder - Circulation research, 2015 - Am Heart Assoc
Hypertension is the most common modifiable risk factor for cardiovascular disease and
death, and lowering blood pressure with antihypertensive drugs reduces target organ …

Expert consensus document from the European Society of Cardiology on catheter-based renal denervation

F Mahfoud, TF Lüscher, B Andersson… - European Heart …, 2013 - academic.oup.com
Hypertension is highly prevalent and one of the most frequent chronic diseases worldwide. 1
It has been suggested that over the next two decades up to 50% of the adult population will …

Sympathetic nervous system and hypertension

GF Dibona - Hypertension, 2013 - Am Heart Assoc
The issue of whether angiotensin II infusion increases renal sympathetic nerve activity was
clarified in studies in conscious rabbits consuming a high NaCl diet. 4 Using a low dose of …

Assembly of staggered ablation elements

A de la Rama, C Hata - US Patent 8,979,839, 2015 - Google Patents
An ablation catheter comprises a catheter body extending longitudinally between a proximal
end and a distal end along a longitudinal axis; and an ablation element assembly …

The carotid body as a putative therapeutic target for the treatment of neurogenic hypertension

FD McBryde, AP Abdala, EB Hendy, W Pijacka… - Nature …, 2013 - nature.com
In the spontaneously hypertensive (SH) rat, hyperoxic inactivation of the carotid body (CB)
produces a rapid and pronounced fall in both arterial pressure and renal sympathetic nerve …