Background Delirium is a common and disturbing postoperative complication that might be
ameliorated by propofol-based anaesthesia. We therefore tested the primary hypothesis that …

It is widely accepted that consciousness or, more generally, mental activity is in some way
correlated to the behavior of the material brain. Since quantum theory is the most …

General anesthesia is a widely used medical practice, affecting more than 300 million
patients annually. Despite its ubiquity, the underlying mechanisms through which anesthetic …

Postoperative cognitive dysfunction (POCD) is a neurological disorder characterized by the
emergence of cognitive impairment after surgery. A growing body of literature suggests that …

Current anesthetic theory is mostly based on neurons and/or neuronal circuits. A role for
astrocytes also has been shown in promoting recovery from volatile anesthesia, while the …

Anesthesia modifies sensory representations in the thalamo-cortical circuit but is considered
to have a milder impact on peripheral sensory processing. Here, tracking the same neurons …

Aging-related reduction in androgen levels may be a possible risk factor for
neurodegenerative diseases and contribute to cognitive impairment. Androgens may affect …

Objective. Intracortical visual prostheses are being developed to restore sight in people who
are blind. The resolution of artificial vision is dictated by the location, proximity and number …

Propofol infusion is processed through the wake-sleep cycle in neural connections, and the
ionotropic purine type 2X7 receptor (P2X7R) is a nonspecific cation channel implicated in …

Introduction Neuropathic pain (NP) conditions arising from injuries to the nervous system
due to trauma, disease, or neurotoxins are chronic, severe, debilitating, and exceedingly …