Recent advances in multifunctional fluorescent probes for viscosity and analytes

X Yang, D Zhang, Y Ye, Y Zhao - Coordination Chemistry Reviews, 2022 - Elsevier
Viscosity has become increasingly important in biological systems, especially as a major
factor in the process of diffusion control. The abnormality of viscosity is closely related to the …

Design and application of fluorescent probes to detect cellular physical microenvironments

J Ma, R Sun, K Xia, Q Xia, Y Liu, X Zhang - Chemical Reviews, 2024 - ACS Publications
The microenvironment is indispensable for functionality of various biomacromolecules,
subcellular compartments, living cells, and organisms. In particular, physical properties …

Lanthanide porphyrinoids as molecular theranostics

GQ Jin, CV Chau, JF Arambula, S Gao… - Chemical Society …, 2022 - pubs.rsc.org
In recent years, lanthanide (Ln) porphyrinoids have received increasing attention as
theranostics. Broadly speaking, the term 'theranostics' refers to agents designed to allow …

Multifunctional Fluorescent Probe for Simultaneous Detection of ONOO, Viscosity, and Polarity and Its Application in Ferroptosis and Cancer Models

L Fan, Q Yang, Q Zan, K Zhao, W Lu, X Wang… - Analytical …, 2023 - ACS Publications
Intracellular peroxynitrite anions (ONOO–) and microenvironments (such as viscosity and
polarity) play an important role in maintaining redox homeostasis, regulating diffusion …

Small molecular fluorescent probes for imaging of viscosity in living biosystems

H Xiao, P Li, B Tang - Chemistry–A European Journal, 2021 - Wiley Online Library
Viscosity, as a vital microenvironment parameter, is tightly associated with multitudinous
cellular processes and diseases. Recently, precise visualization of viscosity has started to …

Real-time monitoring mitochondrial viscosity during mitophagy using a mitochondria-immobilized near-infrared aggregation-induced emission probe

X Wang, L Fan, S Wang, Y Zhang, F Li, Q Zan… - Analytical …, 2021 - ACS Publications
Mitophagy plays a crucial role in maintaining intracellular homeostasis through the removal
of dysfunctional mitochondria and recycling their constituents in a lysosome-degradative …

Dual-channel fluorescent probe for simultaneously detecting H2S and viscosity/polarity and its application in non-alcoholic fatty liver, tumor tissue, and food spoilage

Q Zan, L Fan, L Ma, Q Yang, K Zhao, Y Huang… - Sensors and Actuators B …, 2023 - Elsevier
Intracellular hydrogen sulfide (H 2 S) and micro-environments (eg viscosity and polarity) are
tightly correlated with various physiological/pathological processes, making them potential …

Branching ionizable lipids can enhance the stability, fusogenicity, and functional delivery of mRNA

K Hashiba, Y Sato, M Taguchi, S Sakamoto… - Small …, 2023 - Wiley Online Library
Ionizable lipids with branched tails have been used in lipid nanoparticles (LNPs)‐based
messenger RNA (mRNA) therapeutics like COVID‐19 vaccines. However, due to the limited …

Synergistic effects of multiple rotors and hydrogen-bond interactions lead to sensitive near-infrared viscosity probes for live-cell microscopy

D Li, T Shen, X Xue, W Chen, W Tao, W Chi… - Science China …, 2023 - Springer
Abstract Changes in cellular viscosity are associated with various physiological processes
and pathological conditions. To study these cellular processes and functions, highly …

Rational design of MMP-independent near-infrared fluorescent probes for accurately monitoring mitochondrial viscosity

X Wu, R Zhang, Y Li, Y Gai, T Feng, J Kou… - Analytical …, 2023 - ACS Publications
Mitochondrial viscosity affects metabolite diffusion and mitochondrial metabolism and is
associated with many diseases. However, the accuracy of mitochondria-targeting …