Interest in protein disulfide bond formation has recently increased because of the prominent
role of disulfide bonds in bacterial virulence and survival. The first discovered pathway that …

Natural products that contain functional groups with heteroatom-heteroatom linkages (X–X,
where X= N, O, S, and P) are a small yet intriguing group of metabolites. The reactivity and …

More than one fifth of the proteins encoded by the genome of Escherichia coli are destined
to the bacterial cell envelope. Over the past 20 years, the mechanisms by which envelope …

Salmonella enterica represents an enterobacterial species including numerous serovars
that cause infections at, or initiated at, the intestinal epithelium. Many serovars also act as …

Antimicrobial resistance in Gram-negative bacteria is one of the greatest threats to global
health. New antibacterial strategies are urgently needed, and the development of antibiotic …

Abstract Background In Escherichia coli many heterologous proteins are produced in the
periplasm. To direct these proteins to the periplasm, they are equipped with an N-terminal …

Significance: Recombinant protein production has developed into a huge market with
enormous positive implications for human health and for the future direction of a biobased …

The respiratory pathogen Streptococcus pneumoniae has evolved efficient mechanisms to
resist oxidative stress conditions and to displace other bacteria in the nasopharynx. Here we …

Every bacterial population harbors a small subpopulation of so-called persisters that are
transiently antibiotic tolerant. These persisters are associated with the recalcitrance of …

In animals, plants and the environment, Salmonella enterica serovar Typhimurium forms the
red dry and rough (rdar) biofilm characterized by extracellular matrix components curli and …