Lipid‐based nanoparticles (LBNPs) are currently the most promising vehicles for nucleic
acid drug (NAD) delivery. Although their clinical applications have achieved success, the …

Effective tumor treatment depends on optimizing drug penetration and accumulation in
tumor tissue while minimizing systemic toxicity. Nanomedicine has emerged as a key …

The utilization of plant-derived supplements for disease prevention and treatment has long
been recognized because of their remarkable potential. Ananas comosus, commonly known …

Cancer stem cells (CSCs) are a type of stem cell that possesses not only the intrinsic
abilities of stem cells but also the properties of cancer cells. Therefore, CSCs are known to …

Intravenous administration of drugs is a widely used cancer therapy approach. However, the
efficacy of these drugs is often hindered by various biological barriers, including circulation …

Long-term remission in cancer patients treated with ex vivo bona fide M1-induced
macrophages has been poor, and the reasons behind this are not understood. Injected M1 …

The stratum corneum of the skin presents the initial barrier to transdermal penetration. The
dense structure of the extracellular matrix (ECM) further impedes local drug dispersion …

Solid tumors are composed of a highly complex and heterogenic microenvironment, with
increasing metabolic status. This environment plays a crucial role in the clinical therapeutic …

Nanotechnology shows the power to improve efficacy and reduce the adverse effects of
anticancer agents. As a quinone‐containing compound, beta‐lapachone (LAP) is widely …

While small molecule drugs have gained benefits in tumor targeting delivery from their
nanotherapeutic formulation, the antitumor efficacy of nanomedicines is jointly determined …