Social circuits and their dysfunction in autism spectrum disorder
Social behaviors, how individuals act cooperatively and competitively with conspecifics, are
widely seen across species. Rodents display various social behaviors, and many different …
widely seen across species. Rodents display various social behaviors, and many different …
Social isolation and the brain: effects and mechanisms
An obvious consequence of the coronavirus disease (COVID-19) pandemic is the worldwide
reduction in social interaction, which is associated with many adverse effects on health in …
reduction in social interaction, which is associated with many adverse effects on health in …
Dysfunctional serotonergic neuron-astrocyte signaling in depressive-like states
C González-Arias, A Sánchez-Ruiz, J Esparza… - Molecular …, 2023 - nature.com
Astrocytes play crucial roles in brain homeostasis and are regulatory elements of neuronal
and synaptic physiology. Astrocytic alterations have been found in Major Depressive …
and synaptic physiology. Astrocytic alterations have been found in Major Depressive …
[HTML][HTML] The impact of loneliness and social isolation on the development of cognitive decline and Alzheimer's disease
Alzheimer's Disease (AD) is the leading cause of dementia, observed at a higher incidence
in women compared with men. Treatments aimed at improving pathology in AD remain …
in women compared with men. Treatments aimed at improving pathology in AD remain …
Dynamic influences on the neural encoding of social valence
N Padilla-Coreano, KM Tye… - Nature Reviews …, 2022 - nature.com
Social signals can serve as potent emotional triggers with powerful impacts on processes
from cognition to valence processing. How are social signals dynamically and flexibly …
from cognition to valence processing. How are social signals dynamically and flexibly …
Corticotropin-releasing hormone signaling from prefrontal cortex to lateral septum suppresses interaction with familiar mice
NS de León Reyes, PS Díaz, R Nogueira, A Ruiz-Pino… - Cell, 2023 - cell.com
Social preference, the decision to interact with one member of the same species over
another, is critical to optimize social interactions. Thus, adult rodents favor interacting with …
another, is critical to optimize social interactions. Thus, adult rodents favor interacting with …
Comparing the ontogeny, neurobiology, and function of social play in hamsters and rats
Syrian hamsters show complex social play behavior and provide a valuable animal model
for delineating the neurobiological mechanisms and functions of social play. In this review …
for delineating the neurobiological mechanisms and functions of social play. In this review …
The role of the prefrontal cortex in social interactions of animal models and the implications for autism spectrum disorder
AN Mohapatra, S Wagner - Frontiers in Psychiatry, 2023 - frontiersin.org
Social interaction is a complex behavior which requires the individual to integrate various
internal processes, such as social motivation, social recognition, salience, reward, and …
internal processes, such as social motivation, social recognition, salience, reward, and …
(R)-ketamine restores anterior insular cortex activity and cognitive deficits in social isolation-reared mice
R Yokoyama, Y Ago, H Igarashi, M Higuchi… - Molecular …, 2024 - nature.com
Chronic social isolation increases the risk of mental health problems, including cognitive
impairments and depression. While subanesthetic ketamine is considered effective for …
impairments and depression. While subanesthetic ketamine is considered effective for …
Neural probe system for behavioral neuropharmacology by bi-directional wireless drug delivery and electrophysiology in socially interacting mice
Assessing the neurological and behavioral effects of drugs is important in developing
pharmacological treatments, as well as understanding the mechanisms associated with …
pharmacological treatments, as well as understanding the mechanisms associated with …