Cytotoxic CD4+ T cells eliminate senescent cells by targeting cytomegalovirus antigen
Senescent cell accumulation has been implicated in the pathogenesis of aging-associated
diseases, including cancer. The mechanism that prevents the accumulation of senescent …
diseases, including cancer. The mechanism that prevents the accumulation of senescent …
The small GTPase Arf6: an overview of its mechanisms of action and of its role in host–pathogen interactions and innate immunity
T Van Acker, J Tavernier, F Peelman - International journal of molecular …, 2019 - mdpi.com
The small GTase Arf6 has several important functions in intracellular vesicular trafficking and
regulates the recycling of different types of cargo internalized via clathrin-dependent or …
regulates the recycling of different types of cargo internalized via clathrin-dependent or …
Herpesviruses and the unfolded protein response
BP Johnston, C McCormick - Viruses, 2019 - mdpi.com
Herpesviruses usurp cellular stress responses to promote viral replication and avoid
immune surveillance. The unfolded protein response (UPR) is a conserved stress response …
immune surveillance. The unfolded protein response (UPR) is a conserved stress response …
SNX27: Retromer: ESCPE-1-mediated early endosomal tubulation impacts cytomegalovirus replication
Introduction Cytomegaloviruses (CMVs) extensively reorganize the membrane system of the
cell and establish a new structure as large as the cell nucleus called the assembly …
cell and establish a new structure as large as the cell nucleus called the assembly …
Cytomegalovirus generates assembly compartment in the early phase of infection by perturbation of host-cell factors recruitment at the early endosome/endosomal …
Beta-herpesviruses develop a unique structure within the infected cell known as an
assembly compartment (AC). This structure, as large as the nucleus, is composed of host …
assembly compartment (AC). This structure, as large as the nucleus, is composed of host …
Infection-induced changes within the endocytic recycling compartment suggest a roadmap of human cytomegalovirus egress
Human cytomegalovirus (HCMV) is an important pathogen in developing fetuses, neonates,
and individuals with compromised immune systems. Gaps in our understanding of the …
and individuals with compromised immune systems. Gaps in our understanding of the …
Dynamin inhibitors prevent the establishment of the cytomegalovirus assembly compartment in the early phase of infection
Cytomegalovirus (CMV) infection initiates massive rearrangement of cytoplasmic organelles
to generate assembly compartment (AC). The earliest events, the establishment of the …
to generate assembly compartment (AC). The earliest events, the establishment of the …
Cytomegaloviruses exploit recycling Rab proteins in the sequential establishment of the assembly compartment
Cytomegaloviruses (CMV) reorganize membranous system of the cell in order to develop a
virion assembly compartment (VAC). The development starts in the early (E) phase of …
virion assembly compartment (VAC). The development starts in the early (E) phase of …
Host cell signatures of the envelopment site within beta-herpes virions
H Mahmutefendić Lučin, G Blagojević Zagorac… - International journal of …, 2022 - mdpi.com
Beta-herpesvirus infection completely reorganizes the membrane system of the cell. This
system is maintained by the spatiotemporal arrangement of more than 3000 cellular proteins …
system is maintained by the spatiotemporal arrangement of more than 3000 cellular proteins …
[HTML][HTML] Role of Rab35 in modulating lipid metabolism and viral entry during pseudorabies virus infection
MP Cai, CL Qu, MH Du, SY Wang, GY Yang… - International Journal of …, 2024 - Elsevier
Pseudorabies virus (PRV), the causative agent of Aujeszky's disease in swine, is a
significant pathogen in veterinary medicine. Rab35 is a key regulatory GTPase involved in …
significant pathogen in veterinary medicine. Rab35 is a key regulatory GTPase involved in …