Gregoire, Francine M., Cynthia M. Smas, and Hei Sook Sul. Understanding Adipocyte
Differentiation. Physiol. Rev. 78: 783–809, 1998.—The adipocyte plays a critical role in …

The discovery of leptin in the mid-1990s has focused attention on the role of proteins
secreted by adipose tissue. Leptin has profound effects on appetite and energy balance …

The ability to ensure continous availability of energy despite highly variable supplies in the
environment is a major determinant of the survival of all species. In higher organisms …

It is widely accepted that increasing adiposity is associated with insulin resistance and
increased risk of type 2 diabetes. The predominant paradigm used to explain this link is the …

Background Central obesity results in a cluster of metabolic abnormalities contributing to
premature death. Glucocorticoids regulate adipose-tissue differentiation, function, and …

The importance of a high fat intake in the increasing prevalence of childhood and adult
obesity remains controversial. Moreover, qualitative changes (ie the fatty acid composition of …

Adipose tissue microcirculation is unique within the vascular system because of a capacity
for this tissue to grow throughout most of adult life. A review of the microcirculation of …

The renin‐angiotensin system (RAS) is classically known for its role in regulation of blood
pressure, fluid and electrolyte balance. Recently, several local RASs in organs such as …

BACKGROUND: It is widely accepted that increasing adiposity is associated with insulin
resistance and increased risk of type II diabetes. The predominant paradigm used to explain …

The renin-angiotensin system has long been recognized as an important regulator of
systemic blood pressure and renal electrolyte homeostasis, and local renin-angiotensin …