Vitamin D, best known for its role in skeletal health, has emerged as a key regulator of innate
immune responses to microbial threat. In immune cells such as macrophages, expression of …

The classical function of Vitamin D, which involves mineral balance and skeletal
maintenance, has been known for many years. With the discovery of vitamin D receptors in …

Regulation of immune function continues to be one of the most well recognized extraskeletal
actions of vitamin D. This stemmed initially from the discovery that antigen presenting cells …

The active metabolites of vitamin D3 (D3) and lumisterol (L3) exert a variety of antiaging and
photoprotective effects on the skin. These are achieved through immunomodulation and …

Background: Vitamin D is a secosteroid, which was initially known for its skeletal role;
however, in recent years, its functions in different organs have been increasingly …

The incidence of allergic diseases is increasing, both in developed and developing
countries, concomitantly with the rise in living standards and the adoption of a'western …

Mast cells (MC s) are innate immune cells that are scattered in tissues throughout the
organism being particularly abundant at sites exposed to the environment such as the skin …

Atopic dermatitis (AD) is a chronic skin disorder characterized by pruritus and recurrent
eczematous lesions that are accompanied by T‐helper (Th) 2‐dominated inflammation. AD …

Research has investigated 25-hydroxyvitamin D (25 (OH) D) levels in the Atopic Dermatitis
(AD) population, as well as changes in AD severity after vitamin D (VitD) supplementation …

UV-based phototherapy (including psoralen plus UVA (PUVA), UVB and UVA1) has a long,
successful history in the management of numerous cutaneous disorders. Photoresponsive …