Zebrafish and other small laboratory fishes are emerging as important animal models for
investigating human skeletal development and diseases. In recent years, there has been a …

Purpose of Review GWAS, as a largely correlational analysis, requires in vitro or in vivo
validation. Zebrafish (Danio rerio) have many advantages for studying the genetics of …

This study performed three-dimensional (3D) magnetic resonance imaging (MRI)-based
statistical shape analysis (SSA) by comparing patellofemoral instability (PFI) and normal …

UK Biobank is a large-scale epidemiological resource for investigating prospective
correlations between various lifestyle, environmental, and genetic factors with health and …

Objective The principal aim of this study was to assess an automatic landmarking approach
to human mandibles based on the atlas method. The secondary aim was to identify the …

Genetic diseases affecting the skeletal system present with a wide range of symptoms that
make diagnosis and treatment difficult. Genome‐wide association and sequencing studies …

Geometric morphometrics (GM) enable the quantification of morphological variation on
various scales. Recent technical advances allow analyzing complex three‐dimensional …

Human genetic studies have nominated cadherin-like and PC-esterase domain-containing 1
(CPED1) as a candidate target gene mediating bone mineral density (BMD) and fracture risk …

Abstract Heritable Disorders of Connective Tissues (HDCT) are a heterogenous, pleiotropic
group of conditions that broadly affect connective tissues. EFEMP1 is a member of the fibulin …

First Person is a series of interviews with the first authors of a selection of papers published
in Biology Open, helping early-career researchers promote themselves alongside their …