The important role of endothelium and extracellular vesicles in the cellular mechanism of aortic aneurysm formation

K Mikołajczyk, D Spyt, W Zielińska, A Żuryń… - International journal of …, 2021 - mdpi.com
Homeostasis is a fundamental property of biological systems consisting of the ability to
maintain a dynamic balance of the environment of biochemical processes. The action of …

Stimuli-responsive polymer-doxorubicin conjugate: Antitumor mechanism and potential as nano-prodrug

K Chen, H Cai, H Zhang, H Zhu, Z Gu, Q Gong, K Luo - Acta biomaterialia, 2019 - Elsevier
Polymer-drug conjugates has significantly improved the anti-tumor efficacy of
chemotherapeutic drugs and alleviated their side effects. N-(1, 3-dihydroxypropan-2-yl) …

The response of glandular gastric transcriptome to T-2 toxin in chicks

JJ Luo, Y Zhang, H Sun, JT Wei, MM Khalil… - Food and Chemical …, 2019 - Elsevier
This study was conducted to determine the effect of T-2 toxin on the transcriptome of the
glandular stomach in chicks using RNA-sequencing (RNA-Seq). Four groups of 1-day-old …

Effects of NRP1 on angiogenesis and vascular maturity in endothelial cells are dependent on the expression of SEMA4D

Z Lyu, H Jin, Z Yan, K Hu, H Jiang… - International …, 2020 - spandidos-publications.com
Angiogenesis and vascular maturation play important roles in tumorigenesis and tumor
development. The expression of neuropilin 1 (NRP1) is closely associated with …

Chlorogenic acid enhances intestinal barrier by decreasing MLCK expression and promoting dynamic distribution of tight junction proteins in colitic rats

Z Ruan, S Mi, L Zhou, Y Zhou, J Li, W Liu… - Journal of Functional …, 2016 - Elsevier
The aim of the present study was to evaluate the effect of chlorogenic acid (CGA) on the
mucosal barrier function and tight junction proteins in colitic rats. CGA (60 mg/kg body …

Industrial PM2. 5 cause pulmonary adverse effect through RhoA/ROCK pathway

J Yan, CH Lai, SCC Lung, C Chen, WC Wang… - Science of the Total …, 2017 - Elsevier
Abstract According to the Chinese Ministry of Health, industrial pollution-induced health
impacts have been the leading cause of death in China. While industrial fine particulate …

CRISPR-Based Activation of Endogenous Expression of TPM1 Inhibits Inflammatory Response of Primary Human Coronary Artery Endothelial and Smooth Muscle …

M Gagat, W Zielińska, K Mikołajczyk… - Frontiers in Cell and …, 2021 - frontiersin.org
Tumor necrosis factor α (TNFα) is one of the most important proinflammatory cytokines,
which affects many processes associated with the growth and characteristics of endothelial …

Cytoskeletons of two reproductive germ cell lines response differently to titanium dioxide nanoparticles mediating vary reproductive toxicity

Z Mao, M Yao, B Xu, X Ji, H Jiang, X Han… - Journal of …, 2017 - ingentaconnect.com
Titanium dioxide nanoparticles (TiO2 NPs) have been widely used for many years. Their
toxic effects on the male reproductive system had been reported, but the underlying …

The effect of piperlongumine on endothelial and lung adenocarcinoma cells with regulated expression of profilin-1

M Gagat, M Hałas-Wiśniewska, W Zielińska… - OncoTargets and …, 2018 - Taylor & Francis
Purpose The aim of the study was to evaluate the effect of piperlongumine (2 and 4 µM) on
endothelial EA. hy926 and lung adenocarcinoma A549 cells with regulated expression of …

Genomic organization of repetitive DNAs and differentiation of an XX/XY sex chromosome system in the Amazonian puffer fish, Colomesus asellus (Tetraodontiformes …

PF Viana, T Ezaz, L Marajo, M Ferreira… - … and genome research, 2017 - karger.com
The genus Colomesus is the sole representative of the family Tetraodontidae in the Amazon
region. Here, Colomesus asellus was analyzed using conventional and molecular …